Endometrial Flora in Women Undergoing IVF Treatments
- Conditions
- Endometrial Flora Characterization in Infertile Women
- Registration Number
- NCT03208595
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Brief Summary
Characterization of the female genital tract microbiome in women undergoing IVF treatment
- Detailed Description
The primary goal With The purpose of our study is to examine the uterine microbiome by Next-generation sequencing of the bacteria specific regions .
Vaginal and uterine swabs will be taken in different women undergoing IVF /PGD. Novel bacteria and results of taxonomy assignments will be examine to find correlation of uterine flora with IVF and obstetrical outcomes.
The metagenomics approach will be used to seek previously unidentified bacterial species in the human upper genital tract.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
- All undergoning IVF treatment
- Embryo transfer of one Blastocyst
Exclusion Criteria
- More then one Embryo Transfer
- Recent antibacterial treatment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to assess the feasibility of endometrial sampling in women undergoing embryo transfer by a standart transfer cateteher 2017-2020 Mode of endometrial sampling
To assess endometrial caracteristicas in fertile and infertile women using next generation sequencing of bacterial identification 2017-2020 Type of flora identified by next generation sequencing of bacterial identification
To identify specific endometrial flora in association to faliure of IVF treatment 2017-2020 Type of flora identified by NGS
- Secondary Outcome Measures
Name Time Method