Study of food allergens sensitization in children between age of 5-18 years with respiratory allergic diseases using EAST( enzyme allergo sorbent test) method- a one year hospital based cross sectional study in tertiary care centre

In India, the frequency of immune-mediated illnesses such as allergic airway diseases is rising. Compared to the global average of 7, India has a 2.4-fold higher Death and Disability Associated Life Years (DALY) per case of asthma. Early food sensitization during infancy increases the risk of developing respiratory allergic diseases, including asthma and allergic rhinitis, which account for 10-53% and 29% of cases, respectively, of food sensitization. The most frequently reported dietary allergies were peanuts, milk, and shellfish. Common food allergies in the West include hazelnuts, fruits, and peanuts. The bulk of published research on atopy and allergy disorders originates from high-income English-speaking countries and may not be immediately applicable to low-middle income countries like India due to fundamental differences in genetic, environmental, and lifestyle factors. The use of more recent, less invasive techniques, such as serum IgE antibody detection, has shown to be more sensitive and specific in detecting allergen sensitization profiles, particularly when monitoring the profiles and identifying polysensitization to multiple allergens. There is no scientific evidence to support parents’ concerns that food will harm their child when their child has a respiratory allergy disease, so it’s crucial to inform them of this fact. These parents would benefit from psychological and cognitive therapy to help them strike a balance between the child’s safety and enjoying almost daily life. This study is necessary because, in contrast to more antiquated techniques used in daily practice, it employs a quicker method to identify sensitization profiles of kids with a documented history of allergic airway disease.