NL-OMON46598招募中不适用
Ajmaline provocation in early detection of Arrhythmogenic Cardiomyopathy - Ajmaline provocation in early detection of Arrhythmogenic Cardiomyopathy
niversitair Medisch Centrum Utrecht0 个研究点目标入组 72 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 72
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Age >=18 years
- •Pathogenic PLN mutation, pathogenic PKP2 mutation or patients without structural heart disease who are referred for ajmaline provocation to exclude Brugada syndrome.
- •Referral for cardiac MRI during routine clinical practice
- •New York Heart Association functional class <= 1.
排除标准
- •Severe hepatic impairment (Child-Pugh class C)
- •Severe renal dysfunction (eGFR <30 ml/min/kg)
- •Symptomatic heart failure, NYHA >= 2
- •Women who are currently pregnant
- •Known intolerance or contraindication to Ajmaline
- •Sick sinus syndrome, second or third degree AV block
- •Recent myocardial infarction
- •Known strong allergic reaction to ECG electrodes
- •Current use of anti-arrhythmic drugs (Bruagdadrugs.org list class I, IIa, IIb)
- •Current or recent use of amiodarone (within 6 months)
研究者
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