Morphological and functional analysis of Peyer's patches in inflammatory bowel disease patients by narrow band magnifying enteroscopy
- Conditions
- Patients with inflammatory bowel diseases and patients who are examined by colonoscopy
- Registration Number
- JPRN-UMIN000011633
- Lead Sponsor
- Osaka University Hospital
- Brief Summary
We collected NBI-ME images of PPs from 67 UC patients. The patients were divided into two groups on the basis of villi index: low (L)- and high (H)-types. The time to clinical recurrence was significantly shorter in remissive UC patients with H-type PPs than in those with L-type PPs. Multivariate analysis revealed that the existence of H-type PPs was an independent risk factor for clinical recurrence.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 67
Not provided
1) Patients who were resected ileocecal valve. 2) Patients who take NSAIDs 3) Patients with history of tuberculosis 4) Patients with Behcet disease 5) Patients who were diagnosed as chronic intestinal diseases other than Crohn's disease and ulcerative colitis. 6) Patients with cancer 7) Patients who are undergoing total parental nutrition therapy 8) Patients with severe malnutrition 9) Patients who are not suitable for attending the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The relationship between the changes of Peyer's patches and clinical course of inflammatory bowel disease
- Secondary Outcome Measures
Name Time Method