ACTRN12620000137998已完成2 期
20% Human Albumin Solution Fluid Bolus Administration Therapy in Patients after Cardiac Surgery-II (HAS FLAIR-II): a phase II multicentre randomised controlled trial to determine whether fluid resuscitation with 20% albumin (Albumex®20) in patients after cardiac surgery decreases the duration of vasopressor requirement compared to usual care.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 480
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •The treating clinician wishes to administer fluid bolus therapy (FBT) after cardiac surgery.
排除标准
- •Age less than 18 years
- •Patients who have previously received a FBT prescribed in the ICU after cardiac surgery (NB patients who have received FBT in the ICU prior to surgery remain eligible).
- •Contraindication to study fluid e.g. patients with known or suspected allergy to albumin or crystalloid fluid
- •Documented refusal of any study fluid (i.e. a patient may refuse to receive Human Albumin Solution which is in 20% and 4% albumin)
- •Death is deemed to be imminent or inevitable during this admission, and either the attending physician, patient or substitute decision-maker is not committed to active treatment
- •Off pump cardiac surgery
- •Patient who have previously been enrolled in this study
研究者
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