Effects of Remimazolam on Intraoperative Blood Pressure Control in Interventional Cerebral Aneurysm Coil Embolizatio
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0008343
- Lead Sponsor
- Korea University Anam Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 30
Patients over age 19 undergoing elective cerebral aneurysm coil embolization at Korea University hospital under general anesthesia, who have agreed to terms.
Patients who have already been intubated and sedated before general anesthesia
Patients without tracheal extubation after coil embolization
Patients with hemodynamic instability, such as shock or coma
Patients with hypersensitivity or specific reactions to narcotic drugs, including sevoflurane and remifentanil, and benzodiazepines
Patients who are an absolute contraindication to the administration of remimazolam; Patients with acute narrow-angle glaucoma, patients with acute alcoholism with suppressed vital signs, patients with severe or acute respiratory failure, patients with genetic lactose intolerance such as galactose intolerance, patients with severe hypersensitivity to dextran 40
Patients with mental retardation or difficulties in reading Korean
Subjects who are vulnerable to research (research participants who are vulnerable to coercion or undue influence, or those who lack decision-making ability; pregnant women, fetuses/newborns, minors, those who lack decision-making ability, students, staff, voluntary decision to participate due to surrounding environment susceptible to)
Patients unable to continuously monitor arterial blood pressure through the radial artery
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Intraoperative blood pressure
- Secondary Outcome Measures
Name Time Method Intraoperative heart rate, vasopressor usage, mortality within 30 days POD, delirium 7days POD, AKI 7 days POD (according to KDIGO guideline)