Effects of Recruitment Maneuver on Functional Residual Capacity

Not Applicable

Completed

• Conditions: Anesthesia; Atelectasis; Surgery
• Interventions: Procedure: recruitment maneuver

• Registration Number: NCT04208737
• Lead Sponsor: Istanbul University

Brief Summary

Recruitment maneuver is frequently used in daily anaesthesia routine to prevent athelectasia and ventilation perfusion mismatch. Especially pneumoperitoneum in laparoscopic surgeries affects the functional residual capacity (FRC) negatively. Recently, FRC can be measured at bedside in intensive care units.

The lack of studies evaluating FRC measurements peroperatively and how recruitment maneuvers affect it, attract attention.

Detailed Description

An ICU-ventilator capable to measure the FRC will be used for the mechanical ventilation in patients undergıoing laparoscopic surgery, where anaesthesia maintenance will be achieved with TIVA.

FRC will be measured in different steps of the operation. In the study group, a recruitment manover will be applied to evaluate its effects on FRC.

Study Timeline

• Study First Submitted: 2019-12-16
• Study First Submitted QC: 2019-12-19
• Study Start: 2019-12-23
• Study First Posted: 2019-12-23
• Primary Completion: 2020-05-01
• Status Verified: 2020-06
• Study Completion: 2020-06-01
• Last Update Submitted: 2020-06-07
• Last Update Posted: 2020-06-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1-18-65 years age 2-no lung disease 3-laparoscopic cholecystectomies surgery

Exclusion Criteria

1. <18 years old
2. >65 years old
3. denial of patient
4. patients having one of: lung disease, cardiac failure, severe cardiac valvular disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
study group	recruitment maneuver	5 FRC measurements will be performed We will apply recruitment maneuver two times to patients with 30cmH2O pressure for 15 seconds . First Recruitment maneuver will be applied after the fşrst measurement of FRC following intubation Second Recuitment maneuver will be applied at the end of operation First FRC measurement after anesthesia induction and intubation. Second FRC measurement after first recruitment maneuver Third FRC measurement; after pneumoperitoneum Fourth FRC measurement before second recruitment maneuver Fifth FRC measurement after second recruitment maneuver and at the end of operation

Primary Outcome Measures

Name	Time	Method
Comparison of FRC measurements at beginning and end of anesthesia	within max 5 minutes after the intubation and with max 5 minutes before the extubation	First FRC will be measured after ; the last FRC will be measure bedore the extubation

Secondary Outcome Measures

Name	Time	Method
Positive room air test	in recovery room 30 minutes after operation	in recovery room when patient modified aldrete score ≥ 9 patient SPO2 when breathing in room air If patients' spo2 value ≤ 96%, named as room air test positive

Trial Locations

Locations (2)

Istanbul University; 🇹🇷 Istanbul, Turkey

Istanbul University, Department of Anesthesiology; 🇹🇷 Istanbul, Turkey