PET IN OVARIAN CARCINOMA: AN IAEA INTERNATIONAL COOPERATIVE STUDY
Phase 3
- Conditions
- Health Condition 1: C569- Malignant neoplasm of unspecifiedovary
- Registration Number
- CTRI/2023/03/050433
- Lead Sponsor
- International Atomic Energy Agency (IAEA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients with histologically proven diagnosis of ovarian carcinoma
2.Peritoneal carcinomatosis known or with high suspicion, without known further metastatic spread, before undergoing debulking surgery
3.18F-FDG PET/CT performed prior to surgery less than 4 weeks
4.Signature of informed consent to participate in the study
Exclusion Criteria
1.Metastatic disease known apart from peritoneal carcinomatosis
2.Diabetic patients with bad control
3.Debulking surgery not indicated
4.Surgical contraindications
5. Unable to consent
6. Estimated glomerular filtration rate (eGFR) < 30
7. Claustrophobia
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome will be the diagnostic performance of 18F-FDG PET/CT and its comparison to conventional imaging for staging OC.Timepoint: Within 4 weeks before surgery
- Secondary Outcome Measures
Name Time Method The secondary outcomes include the assessment of prognostic value of different peritoneal carcinomatosis scoring systems and comparison with 18F-FDG PET/CT in ovarian cancer patients. <br/ ><br>Performance of different PET systems and inter reader agreement (using cohenâ??s kappa) will also be assessed.Timepoint: Post surgery follow up