The effectiveness of memantine in patients with Irritable Bowel Syndrome treated with doxepin in quality of life, pain and cognition of ;A double- Blinded Controlled Clinical Trial

Islamic Azad University0 个研究点目标入组 70 人开始时间: 待定最近更新: 2023年2月7日

适应症

试验速览

暂无简介。

•25-65-year-olds who have been experiencing symptoms for more than a year since the onset of symptoms and experiencing symptoms for at least three days a week
•Not taking antidepressants
•Not taking cardiovascular drugs
•No use of corticosteroids.

•One of the side effects of memantine is diarrhea, the prevalence of which is low, mild and transient, but if the patient does not tolerate it, the person will be excluded from the study.
•History of psychotic disorders, bipolar disorders, obsessive compulsive disorders, history of moderate to severe major depression or drug abuse in the last 6 months.
•Patients with suicidal thoughts and attempts.
•People who are pregnant or planning to become pregnant and nursing mothers
•Severe underlying disease
•History of significant weight loss (5% of body weight in six months)
•Gastrointestinal bleeding
•Patients with cardiovascular and respiratory diseases, diabetes, hyperthyroidism
•Liver disorders, seizures
•Urinary retention, benign prostate enlargement
•Allergy to any of the drugs used
•Aggravation of the disease during the study

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