Analysis of the immunological response to coronavirus infectio
Not Applicable
- Conditions
- COVID-19 (SARS-CoV-2 infection)Infections and Infestations
- Registration Number
- ISRCTN63911163
- Lead Sponsor
- niversity of Birmingham
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
Patients and volunteers who have been tested for SARS-CoV-2 infection (both positive and negative for infection) and a matched control group
Exclusion Criteria
Does not meet inclusion criteria
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Presence of immune response to SARS-CoV-2 measured using enzyme-linked immunosorbent assay (ELISA) and direct solid-state protein-binding assays such as Meso Scale Discovery (MSD) at various timepoints depending on the patient<br> 2. Immunological and biological response to SARS-CoV-2 infection and its correlation with clinical outcome, measured using flow cytometry, proteomic analyses and functional studies at various timepoints depending on the patient<br>
- Secondary Outcome Measures
Name Time Method There are no secondary outcome measures