Comparison of Ropivacaine With Dexmedetomidine Versus Magnesium Sulphate In Ultrasound Guided Supraclavicular Brachial Plexus Block For Upperlimb Surgeries.

Phase 4

Not yet recruiting

• Conditions: Unspecified injury of elbow and forearm, (2) ICD-10 Condition: S599||Unspecified injury of elbow and forearm,

• Registration Number: CTRI/2023/07/055203
• Lead Sponsor: Pushpagiri Institute Of Medical Sciences And Research Centre

Brief Summary

Supraclavicular brachial plexus block is considered to be one of the most effective anaesthetic procedures for upperlimb surgeries .In this study we intend to compare the onset and duration of sensory and motor blockade obtained from the administration of 0.75% Ropivacaine with Dexmedetomidine and Magnesium sulphate as adjuvants for this block.The study is conducted in a private medical college setting in Kerala.For this study patients  with distal upperlimb injuries , satisfying the inclusion  criteria are randomly selected to two groups of 26 each using sealed envelope method. Then group A will be given 0.75% Ropivacaine with Dexmedetomidine and group B will be given Ropivacaine with Magnesium Sulphate.The onset of sensory block is defined as Hollman scale of 4 using pinprick.The onset of motor block is defined as achievement of Modified Bromage scale of 3.Duration of sensory block is defined as the time of block to the requirement of rescue analgesia.The duration of motor block is defined as the time of block to the arm raising above the head.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-07-13
• Study Start: 2023-07-24

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

patients undergoing upper limb surgeries under supraclavicular brachial plexus block.Aged between 18 to 65 years and are ASA classes 1 and 2 will be included in the study after obtaining informed consent.

Exclusion Criteria

preexisting peripheral neuropathy .Bleeding disorders.Infection at injection site.Allergy to local anesthetics,magnesium sulphate.surgeries lasting more than 3 hours.Patients with history suggestive of arrythmias.patients who do not give consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time of onset of sensory blockade.	Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
Time of onset of motor blockade.	Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
duration of motor block .	Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.
Duration of sensory block.	Time of onset of sensory blockade assessed at 0 minute,1 minute,3 minutes,5minutes,7minutes,9 minutes,10 minutes likewise every 2 minutes for 20 minutes | Time of onset of motor blockade assessed at 0 minute,1 minute,3 minutes,5 minutes,7 minutes likewise every 2 minutes for 20 minutes | Duration of sensory block assessed at 4 hours,8 hours, 12 hours,16 hours,20 hours,24 hours. | duration of motor block assessed at 4 hours, 8 hours,12 hours, 16 hours , 20 hours , 24 hours.

Secondary Outcome Measures

Name	Time	Method
Hemodynamic stability	monitoring of systolic blood pressure, diastolic blood pressure ,heart rate & oxygen saturation done at o hours,1hour,2hours,3hours,4hours,8hours,12hours,16hours,20hours, 24 hours after administration of supraclavicular brachial plexus block

Trial Locations

Locations (1)

Pushpagiri Institute Of Medical Sciences And Research Centre; 🇮🇳 Pathanamthitta, KERALA, India

Pushpagiri Institute Of Medical Sciences And Research Centre

🇮🇳Pathanamthitta, KERALA, India

Dr Seetha S Prakash

Principal investigator

6238447283

seethasp93@gmail.com