PREVALENCE OF METABOLIC SYNDROME AMONG WOMEN WITH POLYCYSTIC OVARY SYNDROME (PCOS): IMPACT OF LIFESTYLE TREATMENT IN THE MANAGEMENT OF REPRODUCTIVE, ANTHROPOMETRIC, METABOLIC AND QUALITY OF LIFE FACTORS IN PCOS

This randomized controlled trial aims to assess the impact of lifestyle treatment on reproductive, anthropometric, metabolic, and quality of life outcomes in women with Polycystic Ovary Syndrome (PCOS). Participants will be recruited from outpatient facilities of selected hospitals in Vadodara, Gujarat, India. Thirty subjects in the experimental group will receive interpersonal nutritional counseling along with standard care for 60 days, followed by a 60-day washout period, while thirty subjects in the control group will receive only standard care. Data on insulin sensitivity (HOMA-IR), lipid profile, hs-CRP, thyroid profile, reproductive factors (menstrual regularity, ovarian morphology), anthropometric measurements (weight, height, waist circumference, hip circumference, waist-to-hip ratio), psychosocial factors (stress, depression, anxiety), quality of life, and lifestyle factors (physical activity, sleep patterns, diet) will be collected at baseline, after 60 days, and after 120 days. The null hypothesis is that lifestyle treatment may not be effective in improving insulin resistance in PCOS subjects, and the trial will be conducted under the supervision of a gynecologist.