NL-OMON22673
Completed
Not Applicable
Investigating new imaging criteria for non-operative treatment following neoadjuvant chemoradiation in rectal cancer patients
eiden Unversity Medical Center0 sites20 target enrollmentStarted: TBDLast updated:
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- eiden Unversity Medical Center
- Enrollment
- 20
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •Biopsy proven adenocarcinoma of the rectum
- •Patients with locally advanced rectal cancer who, according to current guidelines, are eligible for treatment with neoadjuvant chemoradiation
- •Patients treated in the LUMC, HMC, Alrijne Leiderdorp or Groene Hart Ziekenhuis Gouda.
- •Age 18 years and older;
- •Willing to participate in all aspects of the study
Exclusion Criteria
- •Patients with rectal cancer, receiving chemoradiation as part of the TESAR trial
- •Diabetes mellitus
- •Claustrofobia (low dose benzodiazepines are allowed)
- •Prior radiotherapy to the pelvis
- •If female and fertile: signs and symptoms of pregnancy or a positive pregnancy test / breast\-feeding (a formal negative pregnancy test is not obligatory
- •Presence of any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow\-up schedule
- •Contraindications for Magnetic Resonance Imaging
- •Patient has evidence of infection in the 14 days prior to the FDG\-PET/CT scan localised to the lower abdomen, pelvic region, lower back, inguinal region
- •Inability to tolerate lying supine for the duration of an FDG\-PET/CT examination (\~30min)
Investigators
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