A Study of Electrocardiogram (ECG) Guidance for Placement of Peripherally Inserted Central Catheters (PICC)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Primary Focus: Adult Subjects Who Require PICC Placement
- Sponsor
- C. R. Bard
- Enrollment
- 7
- Locations
- 1
- Primary Endpoint
- Distance of Maximum P-wave Amplitude in Relation to Superior Vena Cava (SVC)/Right Atrium(RA) Junction
- Status
- Terminated
- Last Updated
- 8 years ago
Overview
Brief Summary
This study is designed to obtain information for design purposes on use of an ECG guided monitoring system to aid in the correct placement of PICC lines.
There is no formal study hypothesis.
Detailed Description
PICC line placement is a common procedure, made more difficult by the need to ensure that catheter tip placement is in an acceptable location, typically the superior vena cava (SVC), and ideally at the junction of the SVC and right atrium. Tip location is determined at present by chest X-ray, which is performed after the procedure. If the tip location is incorrect, additional procedures and/or X-rays are needed until proper placement is ensured. Use of an electrode placed inside the catheter during insertion has been reported to provide identifiable changes in the p-wave sufficient to guide placement. This study is designed to collect ECG and catheter depth information during routine PICC placement procedures, and to correlate these ECG changes to tip location as determined by contrast enhanced fluoroscopy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Require Power PICC placement as standard care
- •Signed informed consent
Exclusion Criteria
- •Has an intracardiac device
- •Does not have normal sinus rhythm
- •Has known abnormality of central venous system
- •Plasma creatinine \>=1.5 mg/dL
- •Pregnancy
- •Allergy or prior reaction to contrast material
Outcomes
Primary Outcomes
Distance of Maximum P-wave Amplitude in Relation to Superior Vena Cava (SVC)/Right Atrium(RA) Junction
Time Frame: during catheter insertion
In order to determine correlation of PICC tip location with the intracatheter ECG, the PICC was advanced at 1cm increments and the p-wave observed for amplitude changes.