The effects of multivitamin supplementation on memory and brain function in elderly women experiencing memory decline.

Not Applicable

Completed

• Conditions: Memory decline; Cognitive and memory performance; Brain function; Cardiovascular function; Blood markers of antioxidant status and general health; Mental Health - Studies of normal psychology, cognitive function and behaviour; Neurological - Dementias; Cardiovascular - Normal development and function of the cardiovascular system

• Registration Number: ACTRN12608000256370
• Lead Sponsor: Dr Andrew Pipingas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2008-05-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

Females aged 65- 80 years who are experiencing memory decline.

Exclusion Criteria

Smoking; current supplementation with multivitamins; history of psychiatric disorder, neurological disease, dementia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patterns of brain activity during memory activation tasks using the steady state visually evoked potential (SSVEP) methodology.[Baseline and following 16 weeks supplementation.];Performance on a computerised cognitive task battery. memory performance on standard neuropsychological tasks.[Baseline and following 16 weeks supplementation.]

Secondary Outcome Measures

Name	Time	Method
Blood pressure and augmentation index as measured by the Sphygmocor pulse wave analysis system[Baseline and following 16 weeks supplementation.];Levels of homocysteine; c-reactive protein; fibrinogen; lipids; vitamins B6, B12, C, E and folate; and protein carbonyls in the blood.[Baseline and following 16 weeks supplementation.]