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Evaluation of inhaled medications to improve breathing during exercise in patients with Pulmonary Arterial Hypertensio

Not Applicable
Conditions
pulmonary arterial hypertension
C08.381.423
Registration Number
RBR-66359j
Lead Sponsor
niversidade Federal do Rio Grande do Sul
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Patients diagnosed with pulmonary arterial hypertension according to the Nice classification, 2013, confirmed by right cardiac catheterization at rest. Stable drug treatment in the last 3 months. Symptomatic, with dyspnoea. In functional class of the New York Heart Association II and III.

Exclusion Criteria

Non-HAP Pulmonary Hypertension, that is, Groups 2 to 5 will be excluded, as well as patients with other comorbidities that may cause limitation of exercise capacity. Use of prolonged home oxygen therapy. That they present FEV1VF <0.7. Be involved in regular physical activity programs in the last 3 to 6 months.

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Dyspnea assessed by the Borg categorical scale during isotype (highest common time in all tests) in high intensity constant load ECT (cardiopulmonary exercise test) comparing inhaled bronchodilator, furosemide and placebo.
Secondary Outcome Measures
NameTimeMethod
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