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临床试验/NCT04729153
NCT04729153Unknown不适用

Impact of Previous Treatment of HCV Patients by DAADs on Covid-19 Disease Frequency and Severity

Assiut University0 个研究点目标入组 100 人开始时间: 2021年2月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
入组人数
100
主要终点
Evaluate the effect of DAADs on covid -19

研究概览

简要总结

Evaluate effect of DAADs on covid-19 disease.

详细描述

If Chronic HCV patients who already received DAADs are protected against covid 19 and considered to be immune or not And if DAADS can be used in ttt of covid 19

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • HCV patient with or without LC.
  • >18 years old.
  • Received DAADs at 2019.

排除标准

  • Combined HCV and HIV infected patients.
  • Combined HCV and HBV infected patients.
  • < 18 years old.
  • Pregnant or breast-feeding patients.
  • Patients with autoimmune disease.
  • Patients with multiorgan failure, active cancer, renal insufficiency.
  • Patients received immunosuppressive drugs.
  • Immune compromised patients.
  • Previous confirmed diagnosis of SARS-CoV-2 before starting DAAs.

研究组 & 干预措施

Chronic HCV patients previously treated by DAADs.

干预措施: DAAD Compound (Drug)

结局指标

主要结局

Evaluate the effect of DAADs on covid -19

时间窗: 12 months (from 1/2/2021 to 1/2/2022)

If chronic HCV patients who received DAADs suspected to be infected by covid-19 by having findings suggest covid 19 infection in MSCT chest or clinically symptoms or confirmed by nasopharyngeal swab . And if infected what about severity , if they need hospital admission or oxygen therapy or mechanical ventilation ,if they still alive or died

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Eman Adel Zareh

Doctor

Assiut University

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