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Clinical Trials/NCT04212923
NCT04212923
Recruiting
Not Applicable

EHealth Based Self-management Intervention for Chronic Kidney Disease Care in China

Leiden University Medical Center1 site in 1 country60 target enrollmentOctober 9, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Kidney Diseases
Sponsor
Leiden University Medical Center
Enrollment
60
Locations
1
Primary Endpoint
Change of chronic kidney disease self-management behavior using Chronic Kidney Disease Self-Management (CKD-SM) instrument from baseline to 3, 6 and 9 months after randomization
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to develop an evidence-based tailored eHealth self-management intervention for patients with chronic kidney disease in China, and test the impact on implementation and effectiveness of interventions.

Detailed Description

Interventions that support disease self-management (further referred to as 'self-management interventions') can have a significant impact on the health and quality of life of patients suffering from chronic conditions in general and chronic kidney disease (CKD) patients in specific. In the last decade, the use of electronic health (eHealth) technology in self-management interventions has become more and more popular. EHealth-based self-management interventions have been shown to improve health-related outcomes, such as blood pressure (BP) control and medication adherence, and found to be feasible and acceptable for CKD patients and care professionals. Hence, the use of eHealth self-management interventions for CKD patients has become increasingly popular. Knowledge of the implementation and effectivity of such interventions in China and other developing countries is, however, still lacking. Researchers from the Leiden University Medical Center (LUMC) developed 'Medical Dashboard', an eHealth intervention to help support and involve CKD patients in their disease self-management. We aim to tailor the evidence-based Dutch intervention 'Medical Dashboard' to the Chinese context and evaluate its implementation process and effectiveness.

Registry
clinicaltrials.gov
Start Date
October 9, 2024
End Date
December 30, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Leiden University Medical Center
Responsible Party
Principal Investigator
Principal Investigator

nhchavannes

MD, PhD, Professor of Primary Care Medicine

Leiden University Medical Center

Eligibility Criteria

Inclusion Criteria

  • Patients: (1) aged over 18 years old; (2) diagnosis of chronic kidney disease; (3) Chinese speaking.
  • Health care providers who work in the Department of Nephrology

Exclusion Criteria

  • Individuals unable to participate due to physical or mental disabilities.
  • Individuals unable to write or read.

Outcomes

Primary Outcomes

Change of chronic kidney disease self-management behavior using Chronic Kidney Disease Self-Management (CKD-SM) instrument from baseline to 3, 6 and 9 months after randomization

Time Frame: 0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint)

The Chronic Kidney Disease Self-Management (CKD-SM) instrument with 29 items uses a four-point likert scale ranging from 1 (never) to 4 (always) to measure subjects' self-management behavior. Possible scores range from 29 to 116 points, with higher scores indicating better self-management behavior

Secondary Outcomes

  • Change of blood pressure from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint))
  • Change of body weight from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomization, 6 months after randomization, 9 months after randomization (endpoint))
  • Change of glomerular filtration rate from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint))
  • Change of serum creatinine from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint))
  • Change of number of complications patients have from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint))
  • Change of serum albumin from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint))
  • Hospital admission(9 months after randomisation (endpoint))
  • Change of cost-benefit data from 3 months after randomisation to 9 months after randomisation(3 months after randomisation, 9 months after randomisation (endpoint))
  • Change of chronic kidney disease self-efficacy using Chronic Kidney Disease Self-efficacy (CKD-SE) scale from baseline to 3, 6 and 9 months after randomization(0 month (baseline), 3 months after randomisation, 6 months after randomisation, 9 months after randomisation (endpoint))
  • Change of chronic kidney disease illness perception using Brief Illness Perception Questionnaire (BIPQ) from baseline to 9 months after randomization(0 month (baseline), 9 months after randomisation (endpoint))
  • Change of chronic kidney disease quality of life using the Kidney Disease Quality of Life 36-item short-form survey (KDQOL-36) from baseline to 9 months after randomization(0 month (baseline), 9 months after randomisation (endpoint))
  • Change of chronic kidney disease anxiety and depression status using the Hospital Anxiety and Depression Scale (HADS) from baseline to 3, and 9 months after randomization(0 month (baseline), 3 months after randomisation, 9 months after randomisation (endpoint))
  • Change of healthcare utilisation from 3 months after randomisation to 9 months after randomisation(3 months after randomisation, 9 months after randomisation (endpoint))
  • The proportion of chronic kidney disease patients and care professionals reached by the implementation of interventions(Throughout the 9-month trial)
  • The number of implementation completion tasks completed(Throughout the 9-month trial)
  • The number of chronic kidney disease patients' and care providers' use of the intervention(Throughout the 9-month trial)

Study Sites (1)

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