Effectiveness of Moderate to Vigorous Physical Activity among Stroke risk predicted population- A randomized controlled trial
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 300
- 试验地点
- 3
- 主要终点
- Systolic blood pressure, Hba1c, lipid profile, BMI.
研究概览
简要总结
�’Stroke is the second leading cause of death worldwide, and the leading cause of acquired disability in adults in most regions, countries of low and middle income have the largest burden of stroke accounting for more than 85% of stroke mortality worldwide.
�’In India it is the commonest cause of chronic adult disability. The lifetime risk of stroke after 55 years of age is 1 in 5 for women and 1 in 6 for men. Cardiovascular disease including stroke, which comprised 19% of death nationwide in the year 2001-2003 is estimated to rise to 36% by 2030.
�’The cumulative incidence of stroke ranged from 105 to 152/100000 persons per year and the crude prevalence of stroke ranged from 44.29 to 559/100000 persons in different parts of India during the past decade.
�’Reducing the burden of stroke in the population requires identification of modifiable risk factors and demonstration of the efficacy of risk reduction efforts.
�’There are numerous risk factors for stroke which are both modifiable (hypertension,smoking,diabetes,dyslipidemia, atrial fibrillation,obesity,sedentary lifestyle etc..) and non-modifiable factor(age,gender,family history,race).
�’Estimating stroke risk based on an individual’s particular combination of risk factors, particularly for a first stroke event, is an important component of primary care.
�’Inorder to reduce the stroke incidences it is highly important that the risk factors of stroke are reduced. There are Mass Approaches, target lifestyle modifications and target risk factor reduction programs, observational studies of moderate to vigorous physical activity shows reduction in stroke cases but there is no definite controlled trials performed yet to study the risk factor reduction.
�’Therefore this study on reducing risk factors of stroke by implying moderate to vigorous physical activity among stroke predicted population might be helpful for the society and create an insight for further research.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age above 30 years Both genders Subjects who will be predicted with stroke risk score more than 6% in Stroke Riskometer tool.
- •Subjects willing to participate.
排除标准
- •Previous stroke subjects Subjects with musculoskeletal deformities Subjects with epileptic cases Subjects with other neurological diseases.
结局指标
主要结局
Systolic blood pressure, Hba1c, lipid profile, BMI.
时间窗: Baseline, at mid-term 6th week and at the end of 12th week.
次要结局
- Cooper’s Run test and International Physical Activity Questionnaire.