Clinical study of 5-ASA concentration in colonic mucosa for patients with ulcerative colitis
Not Applicable
- Conditions
- lcerative colitis
- Registration Number
- JPRN-UMIN000031241
- Lead Sponsor
- Keio University Division of Gastroenterology and Hepatology, Department of Internal Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who have been 6 weeks or more past relapse diagnosis. Patients with poor medication adherence for 5-ASA drugs Cases using 5-ASA topical therapy (suppository, enema preparation) within 1 week of endoscopy Patient who used steroid formulation (suppository, enema, oral steroid formulation, steroid injectable formulation) or biologic formulation within 2 weeks of endoscopic enrollment. Patients with Crohn's disease or peptic ulcer Patients with history of colorectal surgery Patients with severe renal and liver impairment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between 5-ASA concentration in colonic mucosa and colonic endoscopic activity
- Secondary Outcome Measures
Name Time Method Correlation between 5-ASA concentration in colonic mucosa and clinical symptoms (Partial UCDAI, DAI, Lichtiger index)