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临床试验/NCT00075972
NCT00075972已完成不适用

CSP #725 - Mood and Smoking: A Comparison of Smoking Cessation Treatments

US Department of Veterans Affairs2 个研究点 分布在 1 个国家目标入组 128 人开始时间: 2003年3月最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
128
试验地点
2

研究概览

简要总结

Objectives:

The long term objectives of this research program are:

  1. To advance the mission of the VHA Boston Healthcare System to deliver comprehensive quality healthcare that meets the needs of patients (in this case, who have been unresponsive to standard smoking cessation treatment) through research and clinical care.
  2. To expand upon our knowledge of the feasibility and effectiveness of commonly-used treatments for nicotine dependence.
  3. To further explore variables related to mood and coping that may contribute to or prevent successful reduction and cessation of smoking behavior among veterans.

The short-term objectives of this project are:

  1. To evaluate the feasibility and effectiveness of two adjunctive treatments (a mood-focused exposure-based treatment, Mood Tolerance, with Nicotine Replacement Therapy [MTNRT] and mood-focused affect-management treatment, Mood Management, with Nicotine Replacement Therapy [MMNRT]) aimed at reduction and cessation of smoking behavior among veterans who were previously non-responders to smoking cessation treatment in the VA.
  2. To inform equivocal findings in the literature regarding the role of mood as trigger for smoking behavior.
  3. To explore selected mood, coping, and individual difference variable that may be predictive of successful abstinence from cigarettes among veterans.

详细描述

Objectives:

The short-term objectives of this project are:

  1. To evaluate the effectiveness of two adjunctive treatments (mood-focused exposure-based treatment, Mood Tolerance, with Nicotine Replacement Therapy [MT-NRT] and mood-focused affect-management treatment, Mood Management, with NRT [MM-NRT] aimed at reduction and cessation of smoking behavior among veterans who were previously non-responders to smoking cessation treatment.
  2. To examine specific variables that may serve as mechanisms of action for successful treatment (i.e., mood and coping variables).

The long-term objectives of this research program are:

  1. To advance the mission of the VA to deliver comprehensive quality healthcare that meets the needs of patients who have been unresponsive to standard smoking cessation treatment, through research and clinical care.
  2. To reduce the exorbitant healthcare costs of nicotine dependence (ND) to the VA, and to improve veterans' physical and psychological well-being, healthcare utilization, and mortality rates.
  3. To evaluate effectiveness of common treatments for ND.
  4. To explore mechanisms of action related to efficacy of treatment for ND among veterans (i.e., changes in mood and coping.)

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
盲法
Single

入排标准

性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

研究者

申办方类型
Fed

研究点 (2)

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