Comparison of Sertraline with Rifampin for treatment of pruritus
Not Applicable
- Conditions
- Condition 1: Primary sclerosing cholangitis. Condition 2: pruritus. Condition 3: Primary biliary cirrhosis.Calculus of bile duct with cholangitisPruritus, unspecifiedPrimary biliary cirrhosis
- Registration Number
- IRCT2015062822956N1
- Lead Sponsor
- Hamedan Univercity of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
inclusion criteria: They should have psc or pbc disease; People have a moderate to severe degree itching; People to participate in the study, are satisfied. exclusion criteria: Unwillingness of patients to participate in study; More than 3-fold increase in liver enzymes and symptoms.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pruritus. Timepoint: before the intervention and after the fourth week measured. Method of measurement: Using visual analog (VAS).
- Secondary Outcome Measures
Name Time Method Direct bilirubin. Timepoint: Before the intervention, and then every two weeks. Method of measurement: Using laboratory findings.;ALP. Timepoint: Before the intervention, and then every two weeks. Method of measurement: Using laboratory findings.;Total bilirubin. Timepoint: Before the intervention, and then every two weeks. Method of measurement: Using laboratory findings.;ALT. Timepoint: Before the intervention, and then every two weeks. Method of measurement: Using laboratory findings.;AST. Timepoint: Before the intervention, and then every two weeks. Method of measurement: Using laboratory findings.