The effect of Sylimarin on insulin resistance and lipid profile in first-degree relatives of diabetic patients

Phase 2

• Conditions: First gegree Relatives of Diabetic Patients.; Diabetes mellitus; E10, E11,

• Registration Number: IRCT201110116430N2
• Lead Sponsor: Yazd Diabetes Research Center, Shahid Sadoughi Univercity of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

First-degree relatives of diabetic patients with BMI >25kg/m2 and age>25 years and age<65 year.
Exclusion criteria: Diabetic patients or first degree relatives with BMI=<25kg/m2 or who consumed drug or supplementation that reduce insulin resistance for past three months.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Insulin. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: inSulin Kit and the Unit is mu/lit.;Lipid profile. Timepoint: Before intervention and 12 weeks after intervention. Method of measurement: Pars Azmoon kit and the Unit is mg/dl.

Secondary Outcome Measures

Name	Time	Method
TG. Timepoint: 12 weeks. Method of measurement: Measurement of blood glucose by Pars Azmoon kit.;LDL. Timepoint: 12 weeks. Method of measurement: Measurement of LDL by Pars Azmoon kit.;HDL. Timepoint: 12 weeks. Method of measurement: Measurement of HDL by Pars Azmoon kit.;Cholesterol. Timepoint: 12 weeks. Method of measurement: Measurement of cholestrol by Pars Azmoon kit.;2hpp. Timepoint: 12 weeks. Method of measurement: Measurement of blood glucose by Auto nalyser method.;FBS. Timepoint: 12 weeks. Method of measurement: Measurement of blood glucose by Auto nalyser method.