Pharmacognostical,Phytochemical study of Hopea parviflora Bedd. and its clinical efficacy in Alasa (Tinea pedis)
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- patient will be assessed on the improvement in clinical features.
研究概览
简要总结
Dermatophytosis also known as Tinea is a fungal infection of the skin. Prevalence of dermatophyte infection in South India is nearly about 27.6%. One such dermatophyte infection commonly seen in the coastal belt of Karnataka is Tine pedis. Environmental factors, agrarian workforce and food habits contribute for the prevalence of this disease in South Canara region. Tinea pedis is the superficial fungal infection affecting the feet, especially inter-digital web spaces. It can be near co-related with Alasa. Alasa is one among the Kshudra rogas mentioned in the Ayurvedic literatures. The growing resistance for the anti-fungal agents in the present scenario has led to rise in the identification of safe herbal drug or formulation which is economical and easily available.
Dipterocarpaceae is dominant family in the evergreen forests of India which are well known for timber, but less acknowledged for its medicinal importance. There is mentioning of few dipterocarpaceae drugs in Ayurvedic texts which are proved potent against many skin diseases. One such dipterocarpaceae member found continuous and through out Western Ghats is Hopea parviflora Bedd. Leaves and stem bark of Hopea parviflora Bedd. are in use in the folklore practice of South Canara. Folklore medicine has given rich contribution to the development of materia-medica of Ayurveda. Integrating these traditional knowledge into mainstream healthcare would require research to understand the efficacy, safety and mechanism of action of traditional medicine. Hence an effort is made to scientifically authenticate the efficacy of drug Hopea parviflora Bedd. in Alasa(Tinea pedis).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients of either sex, between the age group of 16-60 years who will fulfill the diagnostic criteria will be taken up for the study.
排除标准
- •Patients suffering from systemic diseases, Patients taking immuno-suppresive medications, lesions with secondary infections.
结局指标
主要结局
patient will be assessed on the improvement in clinical features.
时间窗: patients will be assessed once in 7 days i.e. on 7th, 14th, 21st, 28th day.
pateints will be assessed as per the subjective parameters- kandu(pruritis), Daha( burning sensation), Ruja( pain) and objective parameters- maceration and fissuring.
时间窗: patients will be assessed once in 7 days i.e. on 7th, 14th, 21st, 28th day.
次要结局
- Patient will be assessed on the improvement in clinical features.(patient will be assessed once in 14days during the follow up period)
研究者
DrKshama Jain
Alvas Ayurveda medical College and Hospital,Moodabidri, DK district
