The Relationship of Bone Mineral Density With Balance, Functional Ambulation and Falls in Stroke Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- Bone mineral density
研究概览
简要总结
The aim of this study is to investigate the relationship between bone mineral density and balance, functional ambulation and falls in hemiparetic patients with stroke in the subacute and chronic phases.
详细描述
Improving balance function is considered as an important method for reducing the risk of falling after stroke and protecting bone health. Bone mineral density, a measure of bone health, has been reported to decrease after stroke, consistent with increased bone resorption and decreased bone formation. The aim of this study is to investigate the relationship between bone mineral density and balance, functional ambulation and falls in hemiparetic patients with stroke in the subacute and chronic phases.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients ≥ 50 and ≤ 75 years old
- •Patients with a 10-year risk of hip fracture ≥3%, major osteoporotic fracture risk ≥20% according to the Fracture Risk Assessment Tool, FRAX, scoring
- •Patients with unilateral hemiplegia as a result of first-time stroke (onset time > 3 months)
- •Patients who can stand for at least 2 minutes independently/under supervision for measurements while standing, and who can walk at least 10 meters independently/under supervision with or without walking aid for measurements taken while walking
- •Patients whose cognitive status is able to understand the study instructions (Mini-Mental State Assessment score ≥ 23)
- •Patients with stable medical and psychological status
- •Patients willing to participate in the study
排除标准
- •Patients with serious cardiovascular or musculoskeletal problems that prevent walking
- •Patients with severe vision, hearing and language problems
- •Patients with other neurological (Parkinson's, epilepsy, meningitis, cerebellar disease, vertigo, dizziness, polyneuropathy, etc.) or musculoskeletal (severe low back pain, knee problems) diseases that may affect balance performance other than stroke.
- •Patients with peripheral vascular disease
结局指标
主要结局
Bone mineral density
时间窗: baseline
Bone mineral density (BMD) will be measured on the lumbar spine (L1-L4) and femoral neck by dual X-ray absorptiometry (DXA) method.
次要结局
- Berg Balance Scale(baseline)
- Timed up and go test(baseline)
- Falls Self-Efficacy Scale(baseline)
- Functional Ambulation Classification(baseline)
研究者
Tuğba Atan, MD
Assoc. Prof
Gaziler Physical Medicine and Rehabilitation Education and Research Hospital