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临床试验/NCT03283332
NCT03283332已完成不适用

Determinants of Adolescent Social Well-being and Health: a London Based Longitudinal Study of Young People From Different Ethnic Groups

King's College London0 个研究点目标入组 6,643 人开始时间: 2011年12月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
6,643
主要终点
Response rate

研究概览

简要总结

Black and ethnic minority groups living in the UK experience high rates of chronic diseases such as diabetes, hypertension and heart disease, general morbidity and poor mental health. The cause of these excess rates is unknown but obesity, smoking, diet and deprivation are important contributing factors. There is also global evidence of the association of these diseases in adulthood with health and deprivation in early life and childhood. Persisting social deprivation over the lifecourse is disproportionately borne by some ethnic minorities (Harding and Balarajan 2001) but the impact on the health of their children is virtually unknown. Least is known about the health of Black Caribbean young people. It is important to examine risk factor differences by social predictors within the ethnic minority groups as well as between them. The DASH Study started as a school-based cohort study of adolescents from the main ethnic groups (White British, Black Caribbean, Black African, Indian, Pakistani and Bangladeshi) in 10 London boroughs. Wave 1 took place in 2002/03 (MREC Ref: MREC/2/10/12), when participants were aged 11-13 years (school years 7 and 8). Wave 2 took place in 2005/06 (MREC Ref: 05/MRE10/43) when they were 14-16 years (school years 9 and 10). Wave 3 took place in 2010/2011, when participants were aged 19-21 years and involved a postal follow-up complemented by telephone interview and on-line questionnaires. The current proposal is for a feasibility study, using a small sample of the DASH cohort, to inform the design of the next full face-to-face follow-up. DASH will be the first large scale UK longitudinal cohort of ethnic minority youths with both social and biological measures from childhood to early adulthood. It will allow detailed examination of ethnic differences in the social patterning of biological mechanisms and pre-clinical disease in young adulthood.

详细描述

Background:

Black and ethnic minority groups living in the UK experience high rates of chronic diseases such as diabetes, hypertension and heart disease, general morbidity and poor mental health. The cause of these excess rates is unknown but obesity, smoking, diet and deprivation are important contributing factors. There is also global evidence of the association of these diseases in adulthood with health and deprivation in early life and childhood. Persisting social deprivation over the lifecourse is disproportionately borne by some ethnic minorities (Harding and Balarajan 2001) but the impact on the health of their children is virtually unknown. Least is known about the health of Black Caribbean young people. It is important to examine risk factor differences by social predictors within the ethnic minority groups as well as between them. The DASH Study started as a school-based cohort study of adolescents from the main ethnic groups (White British, Black Caribbean, Black African, Indian, Pakistani and Bangladeshi) in 10 London boroughs. Wave 1 took place in 2002/03 (MREC Ref: MREC/2/10/12), when participants were aged 11-13 years (school years 7 and 8). Wave 2 took place in 2005/06 (MREC Ref: 05/MRE10/43) when they were 14-16 years (school years 9 and 10). Wave 3 took place in 2010/2011, when participants were aged 19-21 years and involved a postal follow-up complemented by telephone interview and on-line questionnaires. The current proposal is for a feasibility study, using a small sample of the DASH cohort, to inform the design of the next full face-to-face follow-up. DASH will be the first large scale UK longitudinal cohort of ethnic minority youths with both social and biological measures from childhood to early adulthood. It will allow detailed examination of ethnic differences in the social patterning of biological mechanisms and pre-clinical disease in young adulthood.

Aims:

(i) To conduct a feasibility study to establish the best methods for data collection, including the collection of physical and biological measurements, for subsequent face to face follow-up of the entire cohort.

(ii) To generate a proposal for subsequent follow-up of the entire cohort for submission to MRC, dependent on the findings of the postal and telephone surveys and proposed feasibility study.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
11 Years 至 13 Years(Child)
性别
All
接受健康志愿者

入选标准

  • provision of informed consent

排除标准

  • 未提供

结局指标

主要结局

Response rate

时间窗: Through study completion, on average 10 years

Percentage response rates - overall, per item/physical measure

Interview duration

时间窗: Through study completion, on average 10 years

Mean length of time for interview

physical measures duration

时间窗: Through study completion, on average 10 years

Mean length of time for physical/biological measures

次要结局

  • HbA1c(Through study completion, on average 10 years)
  • waist circumference(Through study completion, on average 10 years)
  • HDL-cholesterol(Through study completion, on average 10 years)
  • Fat intake(Through study completion, on average 10 years)
  • Saturated fat intake(Through study completion, on average 10 years)
  • Fibre intake(Through study completion, on average 10 years)
  • Skipping breakfast(Through study completion, on average 10 years)
  • Weight(Through study completion, on average 10 years)
  • Height(Through study completion, on average 10 years)
  • blood pressure(Through study completion, on average 10 years)
  • Body fat(Through study completion, on average 10 years)
  • Energy intake(Through study completion, on average 10 years)
  • Fruit intake(Through study completion, on average 10 years)
  • Fizzy drink intake(Through study completion, on average 10 years)
  • Total cholesterol(Through study completion, on average 10 years)
  • Carbohydrate intake(Through study completion, on average 10 years)
  • Sugar intake(Through study completion, on average 10 years)
  • Sodium intake(Through study completion, on average 10 years)
  • Vegetable intake(Through study completion, on average 10 years)

研究者

申办方类型
Other
责任方
Sponsor

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