CTRI/2010/091/001095
Active, not recruiting
未知
Randomized, double blind, placebo controlled trial to compare the efficacy of 3-months versus 6-months therapy with prednisolone for the first episode of idiopathic nephrotic syndrome in children - None
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- Initial episode of steroid sensitive nephrotic syndrome
- Sponsor
- Indian Council of Medical Research
- Enrollment
- 168
- Status
- Active, not recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Patients with idiopathic, steroid sensitive nephrotic syndrome
- •2\. First episode of nephrotic syndrome
- •3\. Age 1 to 12 years
Exclusion Criteria
- •1\.Nephrotic syndrome known to be secondary to a systemic disorder, e.g., IgA nephropathy, systemic lupus erythematosus, Henoch Schonlein purpura, vasculitis, amyloidosis, hepatitis B antigenemia and Alport syndrome.
- •2\.Patients with impaired renal functions (serum creatinine \> 1\.2 mg/dl, confirmed within 2 weeks)
- •3\.Patients who have received oral prednisolone, in the past for nephrotic syndrome
- •4\.Patients who have taken prednisolone in the past 4 weeks, in a dose more than 1 mg/kg for \>10 days for any other reason
- •5\.Unclear treatment history.
- •6\.Patients staying more than 100 km from the Institute or those not willing to come for clinic visits every two months
- •7\.Gross hematuria
- •8\.Patients with initial steroid resistance
- •9\.Patients who show relapse within the first 3 months of therapy.
Outcomes
Primary Outcomes
Not specified
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