The Effects of Therapeutic Resources on Structure and Function of Normal and Burned Skin
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Elasticity of skin and scar
研究概览
简要总结
Burning produces changes in the biomechanical properties of the skin causing limitation of movement. The increase in skin suppleness is very important in the rehabilitation process, since its increase makes therapeutic interventions aimed at increasing the range of motion, thus improving functional pattern. Will be evaluated 60 volunteers of both sexes aged 20-80 years seen at the Burns Unit of the Clinical Hospital of the Faculty of Medicine of Ribeirão Preto. There will be a traditional physical therapy evaluation as well as evaluation of the specific characteristics of the burn and scar. The temperature of the region will be assessed by thermography, and biophysical parameters and biomechanical skin evaluated by Cutometer and their accessory probes (mexameter, reviscometer, sebometer) before, immediately after and 10, 20 and 30 minutes of application of therapeutic resources. Volunteers will undergo continuous application of ultrasound with 3 MHz and intensity of 1 W/cm2 in the region due to scar deep second degree burn or third degree, and the application time of 2 minutes for each effective radiation area of the head (ERA) in a predetermined region of 9X5 cm a total of 4 minutes of application, therapy paraffin 20 minutes and 4 minutes endermology negative pressure between 100 and 200mmHg, in a continuous mode with glass head (1.5cm in diameter .) Applications will be set by random draw (design crusader cross-over) with an interval of 7 days between applications (wash-out). The data will be submitted to analysis of normality by the Shapiro-Wilk test, and the behavior of the effect between groups and pre-and post-intervention will be evaluated by two-way ANOVA followed by post-hoc (Bonferroni) or Friedman, p <0.05
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Victims of deep second degree burns and third degree with a length of at least 1% of body surface area burned
- •Postoperative graft skin (4 and 6 months)
- •Anywhere in the body that has area to uninjured contralateral control
- •Good state of physical and mental health
- •Aged between 20 and 80 years
- •Both genders
- •Irrespective of race, class or social group
排除标准
- •Volunteers with illnesses or deformities that may interfere with evaluation and procedures
- •Volunteers which do not accept signing the Instrument of Consent and do not meet the inclusion criteria
结局指标
主要结局
Elasticity of skin and scar
时间窗: 3 years
The measurement of skin and scar elasticity will be measured by the used a noninvasive assessment equipment, Cutometer.
次要结局
- Erythema of skin and scar(3 years)
- Fiber direction of skin and scar(3 years)
研究者
Elaine Caldeira de Oliveira Guirro
Professor, PT, PhD
University of Sao Paulo
