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临床试验/CTRI/2024/11/076162
CTRI/2024/11/076162尚未招募不适用

Association of Lumbar Paraspinal Muscle Morphometry in patients with Severe Lower Backache.

SRM1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2024年11月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
SRM
入组人数
64
试验地点
1
主要终点
To assess the cross-sectional areas (CSA) of lumbar paraspinal muscles and their fatty degeneration in adults with spinal pathologies causing severe lower back pain and evaluate their correlations and the changes observed on magnetic resonance imaging (MRI) .

研究概览

简要总结

Purpose :The study provides a basis for Spinal Stabilization excercises and Physiotherapy.Aging leads to atrophy of Muscle Mass and  can be replaced by connective tissues such as fat,which is called Sacropenia,Which occurs with aging.

Methodology :The study is a prospective study. The study population includes all patients with lower backache who underwent MRI.

The patient were divided into two groups :

-Patients with severe spinal pathologies (Degenerative Spondylolisthesis,Disc prolapse,Disc Extrusion)

-Patients without severe spinal pathologies.

In the MRI images,Cross Sectional areas of Multifidus And Erector Spinae We measured by manually tracing the fascial boundaries If the Muscles.

Qualitative measurements of the muscles were obtained between Muscle (low signal) and fast tissue (high signal).

The Functional Cross sectional area(FCSA) : Cross section area ratio &

MF CSA: ES CSA ratio will be calculated and compared between the two groups by using an independent t-test.

Conclusions :

•The  study provides a basis for spinal stabilization exercise and physiotherapy.

•               The MultiFidus muscle is an important stabilizer of the lumbar spine neutral zone, and atrophy of the muscle decreases the ability to control the neutral zone and is strongly associated with Lower Back Pain .

•               Spinal stabilization has been observed to be more effective over time in treating lower back pain than minimal intervention and exercise therapy alone. Therefore, the treatment focus has shifted to reactivation and strengthening of the smaller muscles of the spine to improve long-term stabilization of the vertebral column .

研究设计

研究类型
Observational

入排标准

年龄范围
65.00 Year(s) 至 85.00 Year(s)(—)
性别
Female

入选标准

  • Female sex, Age of 65–85 years, Patients with the Presence of LS.
  • Spine MRI study, The patients with complaints of Polyradiculopathy at the Lumbar.
  • spine level.

排除标准

  • 1.Patients with polyneuropathy, 2.Previous lumbosacral spinal surgery, 3.Systemic disorders, 4.spinal fractures, 5.Tumors, 6.Infections.

结局指标

主要结局

To assess the cross-sectional areas (CSA) of lumbar paraspinal muscles and their fatty degeneration in adults with spinal pathologies causing severe lower back pain and evaluate their correlations and the changes observed on magnetic resonance imaging (MRI) .

时间窗: After taking an MRI Scan

次要结局

  • To see if the functional muscle mass with out the fat degeneration,is decreased in patients with Spondylolisthesis.(After taking an MRI Scan)

研究者

发起方
SRM
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Ashlee Isaac

SRM Medical College and Research Institute

研究点 (1)

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