Expressive Language and Cognitive Early Development in Very Low Birth-Weight Preterm Toddlers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Performance on monthly observations carried out after the initial evaluation
研究概览
简要总结
The aim of the present study is to describe the performance of very low birth-weight preterm toddlers regarding expressive language and cognitive development during sensorimotor and beginning of pre-operational periods, as well as to compare the performance presented by these children to that presented by their full-term peers, according to Genetic Epistemology theoretical principles.
The hypothesis of this study is that very-low birth weight preterms would present a poorer performance, concerning expressive language and cognition development,than their full-term peers.
详细描述
Very low birth weight preterm infants are known to have risks of cognitive and behavioral problems, including learning difficulties, attention deficits and hyperactivity, as well as neuromotor deficits. Moreover, they are reported to have a high risk of speech and language impairments up to school age, even in cases where major neurological abnormalities are excluded. Impairments have been reported both in receptive and expressive language and, more specifically, in morphosyntax and naming.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Month 至 18 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •gestational age lower than 34 weeks (according to the date of last menstrual period - DLMP);
- •birth weight equal or lower than 1500g;
- •exposed only to Brazilian Portuguese
排除标准
- •presence of major malformations, genetic syndromes, severe neonatal asphyxia, hearing impairment or visual impairment.
- •Control Group:
- •Inclusion Criteria:
- •gestational age higher than 38 weeks;
- •adequate for gestational age;
- •birth weight higher than 2500g up to 3999g
- •exposed only to Brazilian Portuguese
- •Exclusion Criteria:
- •pre, peri or post natal intercurrence
结局指标
主要结局
Performance on monthly observations carried out after the initial evaluation
时间窗: 18 months
次要结局
未报告次要终点