Turkish Isolated Coronary Ectasia Prospective Cohort Study: the T-ICE Registry
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,000
- 试验地点
- 1
- 主要终点
- Major adverse cardiovascular and cerebrovascular events
研究概览
简要总结
The T-ICE study is a prospective, observational study aiming to have information about the treatment and long-term prognosis of patients with isolated coronary artery ectasia.
详细描述
Coronary artery ectasia is a localized or diffuse enlargement of the coronary artery lumen ≥1.5-2 times relative to the normal segment. It is often associated with coronary artery stenosis. Some patients have coronary artery ectasia without stenosis. This condition is called as isolated coronary artery ectasia. There is data other than retrospective studies with a small number of cases on the clinical significance, prognosis and treatment of isolated coronary ectasia in patients with or without acute coronary syndrome. Therefore, the treatment of patients with isolated coronary ectasia is not evidence-based and is based on the clinical judgment of physicians. The aim of this prospective observational study is to evaluate the treatment and prognosis of the isolated coronary artery ectasia. The second aim is to compare the prognosis of isolated coronary ectasia with the coronary artery disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Isolated coronary artery ectasia (without ≥20% stenosis in any coronary artery ≥2 mm in diameter).
- •All patients with isolated coronary ectasia with or without acute coronary syndrome will be included.
- •Patients aged ≥18 years.
- •Patients with discrete coronary artery aneurysm will be included.
排除标准
- •Life expectancy <24 months
- •Patients with ≥20% stenosis in a vessel ≥2 mm in diameter.
结局指标
主要结局
Major adverse cardiovascular and cerebrovascular events
时间窗: Five years
A composite endpoint of death, myocardial infarction, unstable angina, stroke, and coronary revascularization.
次要结局
- Major adverse cardiovascular events(Five years)