Comparison of Measured Caloric Expenditure Versus Administered Calories in Neonates
Withdrawn
- Conditions
- Calorie DeficiencyCalorie Overload
- Interventions
- Device: Monitoring of energy expenditure
- Registration Number
- NCT03803657
- Lead Sponsor
- Boston Children's Hospital
- Brief Summary
The investigators have created and validated a device that allows us to accurately measure how many calories a baby consumes every day. The purpose of this study is to compare how many calories a baby consumes with how many calories are provided in a population of newborn infants and children. This may help clinicians to better understand how to feed babies during times of critical illness.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Mechanically ventilated neonates, infants and children, regardless of age, up to 10 kg
- Inpatients in the cardiac (8S), medical-surgical (7S) or neonatal (7N) intensive care unit
- Assent of patient's intensive care attending physician
- Written parental informed consent.
- Patient on conventional mechanical ventilation on a Servo I or Servo U ventilator with fraction of inspired oxygen <80%.
Exclusion Criteria
- Clinically significant tracheo-esophageal fistula
- Measured ETT leak >20% (i.e. difference between inspiratory and expiratory tidal volumes)
- Patient on high frequency oscillatory ventilation or high frequency jet ventilation.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Neonates Monitoring of energy expenditure Neonates 0-28 days Child Monitoring of energy expenditure \>1 year and \<10 kg Infant Monitoring of energy expenditure 29 days to 1 year
- Primary Outcome Measures
Name Time Method Average caloric expenditure through study completion, an average of 3 days Number of calories consumed
- Secondary Outcome Measures
Name Time Method