To compare the duration of postoperative analgesia in patients undergoing Laparoscopic cholecystectomy using Dexmedetomidine and Magnesium sulfate as adjuvants to Bupivacaine in Transversus Abdominis Plane block.

Phase 2

• Conditions: Health Condition 1: K768- Other specified diseases of liver

• Registration Number: CTRI/2024/05/066934
• Lead Sponsor: Vardhman mahavir medical college and Safdarjung hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All Patients belonging to American Society of Anaesthesiologists(ASA) grade I and II and aged between 18–65 years of both genders, undergoing elective laparoscopic cholecystectomy with duration of surgery less than 2 hours are included in the stud

Exclusion Criteria

1. History of allergy to drugs used in the study.

2. Infection or inflammation at the site of block application

3. Pregnant women

4. Those with a BMI of 30 and above.

5. Patients who have cognitive disability or unable to understand the VAS score.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the duration of post operative analgesia (Time to first rescue analgesia as per Visual Analogue Scale for pain) using Magnesium sulphate and Dexmedetomidine as adjuvant to Bupivacaine in ultrasound guided right oblique subcostal Transversus Abdominis Plane Block in patients undergoing Laparoscopic Cholecystectomy.Timepoint: Post operatively at 0 hour , 1 hour, 2 hours, 6 hours, 12 hours, 24 hours

Secondary Outcome Measures

Name	Time	Method
1. To determine the total amount of analgesics consumed in the initial 24 hours . <br/ ><br>2. To evaluate changes in the hemodynamic parameters( Blood pressure and Heart rate) <br/ ><br>during intraoperative period and postoperative period over 24 hours. <br/ ><br>3. To assess post operative sedation using Ramsay Sedation Score.Timepoint: Intra operatively and post operative period