Pilot study of the efficacy of a psychosocial intervention for frequent parasuicide attempters with personality disturbance
Completed
- Conditions
- Mental and behavioural disorders: Other mental disorderMental and Behavioural DisordersPersonality disorder
- Registration Number
- ISRCTN28223466
- Lead Sponsor
- HS R&D Regional Programme Register - Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Efficacy of a new brief manualised form of cognitive behaviour therapy in those with personality disturbance within the flamboyant (cluster B) group. Thirty four patients were enrolled and 32 (18 MACT; 14 TAU) were seen at follow-up.
Exclusion Criteria
Not provided at time of registration.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main outcome measures will be the time of the next parasuicide act (using Linehan's definition of this, which is more minor than an actual suicide attempt). Our expectation is that our experimental treatment will extend this from a mean of three weeks to a mean of three months and this will require a sample size of 30 in each treatment group.
- Secondary Outcome Measures
Name Time Method 1. Time to first suicidal act<br>2. Rate of suicidal acts<br>3. Change in anxiety and depressive symptoms
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie parasuicide behavior in personality disorders as studied in ISRCTN28223466?
How does the psychosocial intervention in ISRCTN28223466 compare to standard-of-care treatments for personality disorders with parasuicidal tendencies?
Are there specific biomarkers identified in ISRCTN28223466 that correlate with response to psychosocial interventions in personality disorders?
What are the potential adverse events associated with intensive psychosocial interventions in frequent parasuicide attempters with personality disturbance?
What combination therapies or alternative approaches are being explored alongside psychosocial interventions for personality disorders in clinical trials?