Hemodynamic monitoring with PulsioFlex ProAQT in the emergency room and burn unit during initial treatment of patients with major burn injuries.

Not Applicable

Recruiting

• Conditions: T20-T32; Burns and corrosions

• Registration Number: DRKS00020826
• Lead Sponsor: BG Klinikum Unfallkrankenhaus Berlin gGmbH (ukb)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-05-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• burn injury with total body surface area (TBSA) =20%, severity of 2nd - 4th degree
• patient's age =18 years
• initial treatmeant in general anesthesia with controlled ventilation

Exclusion Criteria

• relevant cardiac and/or vascular disease which would impede with accurate determination of pre- and afterload via pulse contour analysis (e.g. atrial fibrillation, heart failure, peripheral arterial disease, valvular disease)
• spontaneous breathing
• pregnancy
• rejection of participation in the clinical trial by patient or guardian
• TEN or Lyell- syndrome

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of fluid rescuscitation in total volume and distribution compared to calculated fluid rescuscitation with Parkland/ Baxter formula.

Secondary Outcome Measures

Name	Time	Method
Organ failure, necessity of organ replacement therapy, mortality.<br>Additionally, we plan to examine a possible correlation between initiallly measured pre- and afterload parameters and secondary outcomes.