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Clinical Trials/NCT05207631
NCT05207631
Completed
Not Applicable

Misused Inhaler and Insufficient Peak Inspiratory Flow in Hospitalized COPD Patients Before and After Implementation of a Systematic Assessment and a Prescription Guide - a Quasi Experimental Study - MIPIF

Hôpital Fribourgeois1 site in 1 country101 target enrollmentMarch 1, 2022
ConditionsCOPD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COPD
Sponsor
Hôpital Fribourgeois
Enrollment
101
Locations
1
Primary Endpoint
Proportion of inhalers used sub-optimally at hospital discharge
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The drug treatment of chronic obstructive pulmonary disease (COPD) is mainly based on inhaled therapy. This route of administration is limited by inhaler handling errors, insufficient inspiratory flow or inappropriate inhalers. According to the scientific literature, these limitations are extremely common in both outpatients and inpatients.

Our hypothesis is that the implementation of a standardised and systematic assessment of inhalers combined with a prescribing guide to help select a suitable inhaler will decrease the proportion of suboptimally used inhalers at discharge in patients hospitalised with a diagnosis of COPD.

To assess the effectiveness of our intervention, the investigators will compare the proportion of inhalers used suboptimally at hospital discharge between a control cohort before the implementation of our intervention and a cohort after the implementation of our intervention. Secondary outcomes include reasons for sub-optimal use of inhalers, i.e. inhaler handling errors, insufficient peak inspiratory flow or inappropriate inhaler. Secondary outcomes will also include length of hospital stay and 30-day readmission rate.

Registry
clinicaltrials.gov
Start Date
March 1, 2022
End Date
January 24, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Gaël Grandmaison

Doctor

Hôpital Fribourgeois

Eligibility Criteria

Inclusion Criteria

  • Admission to the HFR Fribourg internal medicine department
  • Age greater than or equal to 18 years
  • Diagnosis of COPD
  • Use of an inhaler device for the treatment of COPD before admission

Exclusion Criteria

  • Inability to complete initial assessment due to language problems
  • Inability to complete initial assessment due to physical or mental conditions
  • Patient who has already received the intervention during a previous hospitalization.
  • Length of hospitalization of less than 72 hours
  • Patient already included in the control period

Outcomes

Primary Outcomes

Proportion of inhalers used sub-optimally at hospital discharge

Time Frame: This outcome is assessed within 48 hours prior to hospital discharge

An inhaler used sub-optimally is defined as an inhaler used with at least one critical error and/or with insufficient inspiratory flow.

Secondary Outcomes

  • Proportion of inappropriate inhaler at hospital discharge.(This outcome is assessed within 48 hours prior to hospital discharge)
  • Proportion of inhaler used with suboptimal peak inspiratory flow at hospital discharge.(This outcome is assessed within 48 hours prior to hospital discharge)
  • Proportion of inhalers used sub-optimally at hospital discharge by type of inhaler.(This outcome is assessed within 48 hours prior to hospital discharge)
  • Length of hospital stay(This outcome is assessed up to three months)
  • Proportion of inhaler used with a critical error at hospital discharge(This outcome is assessed within 48 hours prior to hospital discharge)
  • Proportion of inhalers that cannot be handled properly despite appropriate teaching at hospital discharge.(This outcome is assessed within 48 hours prior to hospital discharge)
  • Proportion of patients using at least one inhaler sub-optimally(This outcome is assessed within 48 hours prior to hospital discharge)

Study Sites (1)

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