Multi-intervention Trial: Improving Inhospital ENDOcarditis Treatment and CARE

Not Applicable

Not yet recruiting

• Conditions: Infective Endocarditis; Heart; Endocarditis, Bacterial; Infection; Bacteremia

• Registration Number: NCT06563609
• Lead Sponsor: Copenhagen University Hospital, Hvidovre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-19
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Inclusion Criteria:<br><br> - Left-sided (native or prosthetic) bacterial infective endocarditis, culture-negative<br> or strong clinical suspicion for endocarditis mandating iv antibiotic treatment in<br> endocarditis-regime, including Cardiac Implantable Electronic Devices (CIED and<br> pacemaker) infections, irrespective of cause and location as defined by the ESC<br> modified Duke Criteria.<br><br> - Age = 18 years.<br><br>Exclusion Criteria:<br><br> - Hemodynamic instability (defined as blood pressure <90 and lactate >2.2 mmol/l<br><br> - Expected to be discharged within 3 days<br><br> - Unwilling or unable to sign informed consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mental health (MH) measured by the standardized Short Form 36 (SF-36)

Secondary Outcome Measures

Name	Time	Method
Grip strength;Quality of life from EQ-5D;Days alive without diarrhoea;Days alive and out of hospital;All-cause mortality;Self-rated mental health