Effect of supplementation in treatment of patients with epilepsy
Phase 3
- Conditions
- Epilepsy.Episodic and paroxysmal disorders
- Registration Number
- IRCT201704225623N110
- Lead Sponsor
- Vice chancellor for research, Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
Aged 2 to 12 years
Patients with epilepsy
Receiving carbamazepine monotherapy
Exclusion Criteria
Taking folate supplements or other therapies such as vitamins or antioxidants within the last 3 months
Unwillingness to cooperate
Metabolic diseases
Chronic medical conditions including anemia and gastrointestinal disease associated with malabsorption
Neuropsychological diseases, and neurodegenerative disorders
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Carotid intima-media thickness. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Sonography.
- Secondary Outcome Measures
Name Time Method itric oxide. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Spectrophotometry.;Malondialdehyde. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Spectrophotometry.;Hs-CRP. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Elisa kit.;Total antioxidant. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Spectrophotometry.