Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement. A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- ISQ measurement for implant stability
研究概览
简要总结
The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.
详细描述
A comparative study for ridge augmentation procedure, With two groups. First group underwent a surgical ridge splitting procedure with ultrasonic bone surgery and grafting with Xenograft alone and implant placement. Second group underwent a surgical ridge splitting procedure with ultrasonic bone surgery Xenograft mix ed with Arginylglycylaspartic acid (RGD) and implant placement.
Both groups were followed up for 1 and 3 months after loading.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults (age 18-30) exhibiting initial insufficiently bone width.
- •Patients with good oral hygiene.
- •Patients must be free from systemic diseases that may influence the outcome of the therapy.
- •Patients with bony horizontal defects alone, Class III & IV.
排除标准
- •Heavy smokers.
- •Patient treated by immunosuppressive chemotherapy or radio therapy,
- •Allergy to any material or medication used in the study.
- •Pregnant females.
研究组 & 干预措施
Control Group
Xenograft alone with split-crest technique by ultrasonic bone surgery and implant placement.
干预措施: Xenograft (Drug)
Control Group
Xenograft alone with split-crest technique by ultrasonic bone surgery and implant placement.
干预措施: Split crest technique (Procedure)
Study Group
Xenograft mixed with RGD with split-crest technique by ultrasonic bone surgery and implant placement.
干预措施: RGD (Drug)
Study Group
Xenograft mixed with RGD with split-crest technique by ultrasonic bone surgery and implant placement.
干预措施: Xenograft (Drug)
Study Group
Xenograft mixed with RGD with split-crest technique by ultrasonic bone surgery and implant placement.
干预措施: Split crest technique (Procedure)
结局指标
主要结局
ISQ measurement for implant stability
时间窗: At time of surgery, at loading and 3 months after loading.
Evaluate implant stability by osstell device
次要结局
- Bone density around dental implants.(At time of loading and 3 months after loading)
研究者
muhammed nagy
Principle investigator
Al-Azhar University