Identification of Risk Factors for Atrial Fibrillation After Ablation of an Atrial Flutter by Radiofrequency of the Cavotricuspid Isthmus.
- Conditions
- Flutter
- Registration Number
- NCT03919097
- Lead Sponsor
- José Castro
- Brief Summary
Atrial flutter is a common condition that is effectively treated by ablation using radiofrequency. Due to its feasibility, effectiveness and low procedural risk, radiofrequency ablation is a first-line treatment of atrial flutter.
Several studies have been published concerning the factors associated with the occurrence of atrial fibrillation during or after flutter ablation, in patients with and without clinical history of atrial fibrillation. 26 to 46% of patients are likely to develop it, according to ECG or Holter diagnoses. The figure rises to more than 50% with a diagnosis with an implantable loop recorder.
In patients without a prior history of atrial fibrillation before ablation, anticoagulants are routinely administered 4-6 weeks after flutter removal by most cardiologists.
Although there are no specific guidelines for anticoagulation after flutter ablation, it is currently recommended to treat the patient as for atrial fibrillation. It is therefore crucial to identify in advance patients at high risk of atrial fibrillation after flutter ablation, in order to assess the appropriateness of maintaining oral anticoagulant therapy.
The objectives of this study are:
* to evaluate the frequency and identify the factors predicting the occurrence of atrial fibrillation after flutter ablation
* to determine the risk of a stroke occurring in patients with atrial fibrillation after flutter ablation.
The database consists in patients of the CHU Brugmann Hospital treated between 1996 and 2018.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Patients treated at the CHU Brugmann Hospital for flutter ablation by radiofrequency between 1996 and 2018.
None
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cardiac surgery antecedents One day Presence of cardiac surgery antecedents at the date of flutter ablation
Age at ablation One day Age of the patient at the date of the flutter ablation
Gender One day Gender of the patient at the date of the flutter ablation
Antecedents of ischemic cardiomyopathy One day Antecedents of ischemic cardiomyopathy (yes/no) at the date of flutter ablation
Antecedents of dilated cardiomyopathy One day Antecedents of dilated cardiomyopathy (yes/no) at the date of flutter ablation
Chronic pulmonal disease One day Chronic pulmonal disease diagnosed at the date of flutter ablation
Stroke after flutter ablation One year Occurence of stroke after the flutter ablation
Diabetes One day Diabetes diagnosis (yes/no) at the date of flutter ablation
Arterial hypertension One day Presence of arterial hypertension on the day of flutter ablation
Antecedents of stroke One day Antecedents of stroke
Antecedents of peripheric thromboembolic events One day Antecedents of thromboembolic events on the day of flutter ablation
Antecedents of cardiomyopathy One day Antecedents of cardiomyopathy (yes/no) at the date of flutter ablation
Atrial fibrillation antecedents One day Antecedents of Atrial fibrillation at the date of flutter ablation
Peripheric thromboembolic events after flutter ablation One year Thromboembolic events after flutter ablation
Left ventricular ejection fraction of the heart One day Left ventricular ejection fraction of the heart at the day of flutter removal (echographic data)
Beta-blockers post-ablation One day Prescription of Beta-Blockers after the flutter ablation (yes/no)
Amiodarone post-ablation One year Prescription of amiodarone after the flutter ablation (yes/no)
Left atrium size of the heart One day Left atrium size of the heart at the day of flutter removal (echographic data)
Class I antiarrhythmic drugs post-ablation One year Prescription of Class I antiarrhythmic drugs post-ablation
Pulmonary arterial pressure One day Pulmonary arterial pressure at the day of flutter removal (echographic data)
Atrial Fibrillation apparition delay Up to one year Delay of apparition of atrial fibrillation after flutter removal
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
CHU Brugmann
🇧🇪Brussels, Belgium
CHU Brugmann🇧🇪Brussels, Belgium