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Clinical Trials/NCT05820750
NCT05820750
Enrolling By Invitation
Not Applicable

Clinical and Radiographic Evaluation of Photodynamic Therapy for Root Canal Treatment of Primary Molars

Mansoura University1 site in 1 country60 target enrollmentDecember 1, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Photodynamic Therapy
Sponsor
Mansoura University
Enrollment
60
Locations
1
Primary Endpoint
Evaluation of clinical success of photodynamic therapy
Status
Enrolling By Invitation
Last Updated
3 years ago

Overview

Brief Summary

This study will be conducted to evaluate clinical and radiographic success of Photodynamic Therapy for root canal treatment of primary molars in comparison to the standard root canal treatment.

Registry
clinicaltrials.gov
Start Date
December 1, 2022
End Date
May 1, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohamed Elsayed Abo Farrag

assistant lecturer at paediatric dentistry department

Mansoura University

Eligibility Criteria

Inclusion Criteria

  • Children aged 4-7 years.
  • Apparent healthy child not suffering from any mental or physical disability.
  • Cooperative children.
  • Restorable teeth.
  • Each child should have at least one carious primary molar with signs and symptoms of irreversible pulpitis or pulp necrosis.
  • Absence of internal and / or external perforation in the furcation area.
  • At least 2/3 thirds of the roots should be remained.

Exclusion Criteria

  • Children with compromised health or physical disability.
  • Resorption of the roots more than 2/3 thirds.
  • Non restorable teeth.

Outcomes

Primary Outcomes

Evaluation of clinical success of photodynamic therapy

Time Frame: 14 months

The following criteria will be used for the determination of treatment success or failure: 1. Repair (= success) Clinically: absence of signs and symptoms. 2. Lack of repair (= failure) Clinically: signs and symptoms indicative of acute apical periodontitis.

Evaluation of radiographic success of photodynamic therapy

Time Frame: 14 months

The following criteria will be used for the determination of treatment success or failure: 1. Complete repair (= success) Radiographically: absence of pathological root resorption, normal width of periodontal ligament space, absence of lesion development in periapical regions in cases of absence of lesion in the initial diagnostic radiograph and complete regression of lesion in cases of presence of lesion in the initial diagnostic radiograph. 2. Incomplete repair (= success) Radiographically: absence of pathological root resorption and reduction lesion size in the periapical region. 3. Lack of repair (= failure) Radiographically: presence of pathological root resorption, lesion in furcation/periapical region unchanged in size during follow-up period, increase in lesion size or the development of a new lesion.

Study Sites (1)

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