ACTRN12618000561280已完成未知
Relation between chronic endometritis and recurrent miscarriage
Department of Obstetrics and Gynecology, Ahmadi hospital, Kuwait.0 个研究点目标入组 110 人开始时间: 2018年4月13日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 110
研究概览
简要总结
Summary of results: The prevalence of chronic endometritis in women with recurrent miscarriage was 31.8% using chronic endometritis-related hysteroscopic signs, while it was 38.2% using immunohistochemical staining and endometrial cultures (p = 0.4). Chronic endometritis-related hysteroscopic signs had 64.1% sensitivity, 85.9% specificity, 71.4% positive predictive value (PPV), 81.3% negative predictive value (NPV), and 78.2% overall accuracy in diagnosing chronic endometritis. Most cases of chronic endometritis (> 81%) were caused by Mycoplasma and common pathogens.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Diagnosis
入排标准
- 年龄范围
- 20 Years 至 40 Years（—）
- 性别
- Female
入选标准
- •Patients and methods: Analysis of the hospital records over the last 5 years from January 2012 to January 2017 to identify women with unexplained recurrent miscarriage, after approval of the Obstetrics and Gynecology department.
- •Inclusion criteria includes; women who will give consent, >20-40 years, with 3 or more miscarriages before 22 weeks’ gestation.
排除标准
- •Exclusion criteria includes; family history of RM, uterine abnormalities, hormonal or metabolic disorders, severe male factor infertility, previous surgery for myoma and/or endometriosis, clinical or ultrasound diagnosis of endometriosis, known clinical autoimmune disease, anti-phospholipid syndrome (APS), thrombophilic condition requiring anticoagulant therapy, and unwilling to give informed consent.
研究者
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