europsychological intervention in Parkinson's disease

Not Applicable

• Conditions: G20; Parkinson disease

• Registration Number: DRKS00004978
• Lead Sponsor: Institut für GerontologieUniversität Vechta

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-05-29
• Study Completion: 2014-01-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Patients with a clinical diagnosis of idiopathic Parkinson's disease (UK Brain Bank Criteria; Hughes et al., 1992).
Patients, who score I-III on Hoehn and Yahr scale.
Patients, without dementia (without cognitive impairment, mild cognitive impairment in accord with Petersen at most) with a Demtect score > 8 and MMSE > 24.
Male and female patients.
Patients at the age of 50 to 90.
Patients without significant impairment of hearing or sight.
Native german-speaking patients, or patients with a sufficient knowledge of the german language.
Patients, who are able to participate in the training session (90 minutes, 2 times a week over 6 weeks).
Patients, who participate in minimum 8 of 12 sessions.
Patienten, who give their consent to participate in the study and who sign informed consent.

Exclusion Criteria

Patients with suspected dementia (DemTect < 9, MMSE < 25).
Patients with another neurological (e.g. epilepsy, Alzheimer's disease) or psychiatric disease (schizophrenia).
Patients with drug or alcohol abuse (at present or in the past).

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effects on cognitive total scores (DemTect, MMSE). The primary outcomes are examined at T0 (pretest), T1 (examination after the intervention or after 6 weeks without intervention), T2 (one year follow-up), T3 (2 year follow-up).

Secondary Outcome Measures

Name	Time	Method
Effects on <br>1. cognitive subdomains: attention (Brief test of attention); verbal short and long term memory (DemTect Memo-test); visual memory (Rey-Osterrieth figure / Modified Taylor figure); visuoconstructive skills (Rey-Osterrieth figure / Modified Taylor figure); working memory (DemTect).<br>verbal fluency (DemTect, FAS-test); subjective memory impairment (Memory Complaint Questionnaire); subjective attention impairment (Fragebogen erlebter Defizite der Aufmerksamkeit).<br>2. non-cognitive parameters: depression (BDI-II); quality of life (PDQ-39).<br>Secondary outcomes are examined at T0 (pretest), T1 (examination after the intervention or after 6 weeks without intervention), T2 (one year follow-up), T3 (2 year follow-up).