NCT05301634已完成3 期
Comparison Between Hemodynamic Effect of Bilateral Infraorbital Block Versus Intranasal Application of Bupivacaine in Patients Undergoing Transsphenoidal Pituitary Adenoma Resection.A Comparative Randomized Controlled Study
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Mean arterial blood pressure
研究概览
简要总结
The study will evaluate the efficacy of bilateral infraorbital nerve block versus preoperative nasal packing with long-acting local anesthetic bupivacaine in term of maintaining hemodynamics intraoperative within 20% below baseline to achieve adequate hypotensive anesthesia and longer duration of postoperative analgesia up to 24 hours in patients undergoing transsphenoidal pituitary adenoma resection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I, II or III
- •patients scheduled to undergo endoscopic transsphenoidal approach to remove tumor under general anesthesia
排除标准
- •Patient's refusal
- •Allergy to local anesthetics.
- •Preoperative cerebrospinal fluid leak.
- •Preoperative cardiac arrythmias.
- •Seizure disorders.
- •Patients with severe endocrinal disorders that affecting the craniofacial morphology as acromegaly and cushinoid features.
结局指标
主要结局
Mean arterial blood pressure
时间窗: at the time of mucosal dissection
次要结局
- Intraoperative need for nitroglycerine(the entire duration of surgery)
- Postoperative need of pethidine(24 hours postoprative)
- Intraoperative need for magnesium sulphate(the entire duration of surgery)
- Intraoperative need for fentanyl(the entire duration of surgery)
- Postoperative pain assessed by Numeric pain score(24 hours postoprative)
研究者
AbdElKhalik Mahmoud Shaban
Lecturer of anaesthesia
Cairo University
研究点 (1)
Loading locations...
相似试验
已完成
不适用
The Effect of Bilateral Infraorbital+ Infratrochlear Nerve Block for Rhinoplasty OperationsAnesthesia, LocalNCT05671237Istanbul University60
Unknown
4 期
Effect of Infraorbital and Infratrochlear Nerve Block on Emergence Agitation in Patients Undergoing SeptorhinoplastyEmergence AgitationPainNCT02751268Armed Forces Hampyeong Hospital66
招募中
不适用
Sternotomy PIFB Block in Open Heart SurgeryAutonomic Nerve BlockNCT06233318Ohio State University84
尚未招募
1 期
Study to find out changes in heart rate and blood pressure when two different lubricants are put in nose to pass a tube to stomachCTRI/2020/01/022945Amrita Institute of Medical Sciences
尚未招募
Unknown
Bilateral scalp block on intraoperative opioid consumption, postoperative pain and intra and postoperative hemodynamics in children undergoing supratentorial craniotomy under general anaesthesiaCTRI/2023/07/055812AIIMS, New Delhi