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Randomised controlled trial on efficacy and safety of short term versus long term antibiotic therapy for pyelonephritis in childhood. - Short term antibiotic therapy for pyelonephritis in childhood.

Conditions
Acute pyelonephritis
MedDRA version: 9.1Level: LLTClassification code 10037596Term: Pyelonephritis
Registration Number
EUCTR2008-003209-16-IT
Lead Sponsor
ISTITUTO PER L'INFANZIA BURLO GAROFOLO
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Children aged 1 month to 5 years, with a first episode of upper urinary infection (pyelonephritis).
Are the trial subjects under 18? yes
Number of subjects for this age range:
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Children less than 1 month, or older than 5 years.
Relapse of pyelonephritis.
Sepsis and/or vomiting, or other conditions where it?s impossible to administer an oral therapy.
Allergy to ceftibuten.
Previous antibiotic therapy for the same infection.
Long term antibiotic prophylaxis with an antibiotic of the same class, if laboratory antibiotic resistance is shown.
Children with uncontrolled other disease.
Complicated pyelonephritis (abscess).

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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