Skip to main content
Clinical Trials/NCT05994768
NCT05994768
Completed
Not Applicable

Comparison of the Performance of 18F-FDG PET/CT With That of Labeled Leukocyte Scintigraphy in the Follow-up of Malignant Otitis Externa.

Central Hospital, Nancy, France1 site in 1 country18 target enrollmentDecember 18, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Malignant Otitis Externa
Sponsor
Central Hospital, Nancy, France
Enrollment
18
Locations
1
Primary Endpoint
18F-FDG positron emission tomography
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The study will aim to show that there is a superiority of 18F-FDG PET/CT compared to labeled leukocyte scintigraphy in patients with a malignant otitis externa.

Detailed Description

The management of malignant otitis externa (MEO) is a major issue in patients who are often polypathological and fragile. Appropriate antibiotic therapy must be started quickly after the diagnosis is made and followed for a period of at least 6 weeks. Imaging plays a major role in assessing the extent of the infection and especially healing, after 6 weeks of antibiotic therapy. The persistence of an infection at the end of the treatment, observed in imaging, will allow a change of antibiotic line. This study consists in studying in a population affected by an OEM, the performance of PET/CT with 18F-FDG compared to scintigraphy with labeled leukocytes. The usefulness of the latter in the follow-up of the pathology after antibiotic therapy has already been proven in the literature. The study will aim to show that there is a superiority of 18F-FDG PET/CT compared to labeled leukocyte scintigraphy.

Registry
clinicaltrials.gov
Start Date
December 18, 2020
End Date
October 18, 2023
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Central Hospital, Nancy, France
Responsible Party
Principal Investigator
Principal Investigator

Antoine VERGER

MD, PhD

Central Hospital, Nancy, France

Eligibility Criteria

Inclusion Criteria

  • patients with malignant otitis externa who received a 18F-FDG positron emission tomography and a labelled leukocyte scintigraphy

Exclusion Criteria

  • patients who refuse to have their imaging data used

Outcomes

Primary Outcomes

18F-FDG positron emission tomography

Time Frame: one day

measurement of standard uptake value

Labeled leukocyte scintigraphy

Time Frame: one day

measurement of standard uptake value

Study Sites (1)

Loading locations...

Similar Trials