Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City

Not Applicable

Completed

• Conditions: Chronic Respiratory Diseases
• Interventions: Other: Questionnaire; Device: Lung function test

• Registration Number: NCT02898129
• Lead Sponsor: Brugmann University Hospital

Brief Summary

The research question is "Are the different types of house in Ho Chi Minh city equally contributing to chronic respiratory diseases?".

According to this question, a cross-sectional and explorative study was set up to explore the differences in the environmental characteristics and prevalence of chronic respiratory diseases among common housing types in Ho Chi Minh city. Preliminary work was performed in 100 houses (20 houses per type, included tube houses, rental houses, rural houses, slum and apartment) from November 2013 to June 2015. It included measures by environmental devices, questionnaires and indoor activities diaries.

This study will aim to collect information about the prevalence of chronic respiratory diseases (CRDs) inside those house types to understand more about role of house types in developing CRDs.

The objective is:

1. to evaluate the relationships between the type of house and lung function of inhabitants in each housing type.

2. to evaluate the effects of environmental risk factors in each house type on prevalence of CRDs

Detailed Description

Not available

Study Timeline

• Study Start: 2016-09
• Study First Submitted: 2016-09-08
• Study First Submitted QC: 2016-09-08
• Study First Posted: 2016-09-13
• Primary Completion: 2017-07
• Study Completion: 2017-07
• Status Verified: 2017-08
• Last Update Submitted: 2017-08-03
• Last Update Posted: 2017-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1500

Inclusion Criteria

• Everybody

Exclusion Criteria

• Not able to answer the questionnaire or give informed consent
• Have a contra-indication for lung function test (acute myocardial infarction less that 1 month ago, pain related to spirometry, dementia/confused)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Tube houses	Questionnaire	Tube Houses. Group of 75-100 houses, with 4 inhabitants per house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
Apartment	Lung function test	Apartments. Group of 75-100 apartments, with 4 inhabitants per apartment. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
Rural houses	Questionnaire	Rural Houses. Group of 40-60 rural houses, with 5 inhabitant per rural house. Expected number of participants: 200-300. Predicted number of non-smoker chronic respiratory disease of 12-18.
Rental Houses	Lung function test	Rental Houses. Group of 150-200 rental houses, with 2 inhabitants per rental house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
Tube houses	Lung function test	Tube Houses. Group of 75-100 houses, with 4 inhabitants per house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
Rental Houses	Questionnaire	Rental Houses. Group of 150-200 rental houses, with 2 inhabitants per rental house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
Apartment	Questionnaire	Apartments. Group of 75-100 apartments, with 4 inhabitants per apartment. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
Rural houses	Lung function test	Rural Houses. Group of 40-60 rural houses, with 5 inhabitant per rural house. Expected number of participants: 200-300. Predicted number of non-smoker chronic respiratory disease of 12-18.

Primary Outcome Measures

Name	Time	Method
FEV1/FVC	5 minutes	Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test. FEV1: forced expiratory volume in one second. FVC: Forced vital capacity.
FVC	5 minutes	Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test.FVC: Forced vital capacity.
VC	5 minutes	Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes performed during the same test. VC: Vital capacity
FEF 25-75%	5 minutes	Basic lung function test, without broncho dilatation (micro-spirometer).All lung function related outcomes are performed during the same test. FEF: Forced expiratory flow
Socio-demographic status	around 10 minutes	Socio-demographic data, assessed by a home made questionnaire
Health status	around 10 minutes	Health status (symptomatology) data, assessed by a home made questionnaire
Indoor air exposure time	around 10 minutes	Indoor air exposure (time spent indoor within housing types, with associated air characteristics) data, assessed by a home made questionnaire

Trial Locations

Locations (1)

Pham Ngoc Thach University of medicine; 🇻🇳 Ho Chi Minh City, Vietnam