Evaluating the Relationship Between Environmental Risk Factors in Housing Types and Chronic Respiratory Diseases in Ho Chi Minh City
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,500
- 试验地点
- 1
- 主要终点
- FEV1/FVC
研究概览
简要总结
The research question is "Are the different types of house in Ho Chi Minh city equally contributing to chronic respiratory diseases?".
According to this question, a cross-sectional and explorative study was set up to explore the differences in the environmental characteristics and prevalence of chronic respiratory diseases among common housing types in Ho Chi Minh city. Preliminary work was performed in 100 houses (20 houses per type, included tube houses, rental houses, rural houses, slum and apartment) from November 2013 to June 2015. It included measures by environmental devices, questionnaires and indoor activities diaries.
This study will aim to collect information about the prevalence of chronic respiratory diseases (CRDs) inside those house types to understand more about role of house types in developing CRDs.
The objective is:
- to evaluate the relationships between the type of house and lung function of inhabitants in each housing type.
- to evaluate the effects of environmental risk factors in each house type on prevalence of CRDs
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 10 Years 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Everybody
排除标准
- •Not able to answer the questionnaire or give informed consent
- •Have a contra-indication for lung function test (acute myocardial infarction less that 1 month ago, pain related to spirometry, dementia/confused)
研究组 & 干预措施
Tube houses
Tube Houses. Group of 75-100 houses, with 4 inhabitants per house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
干预措施: Questionnaire (Other)
Tube houses
Tube Houses. Group of 75-100 houses, with 4 inhabitants per house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
干预措施: Lung function test (Device)
Apartment
Apartments. Group of 75-100 apartments, with 4 inhabitants per apartment. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
干预措施: Questionnaire (Other)
Apartment
Apartments. Group of 75-100 apartments, with 4 inhabitants per apartment. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
干预措施: Lung function test (Device)
Rental Houses
Rental Houses. Group of 150-200 rental houses, with 2 inhabitants per rental house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
干预措施: Questionnaire (Other)
Rental Houses
Rental Houses. Group of 150-200 rental houses, with 2 inhabitants per rental house. Expected number of participants: 300-400. Predicted number of non-smoker chronic respiratory disease of 18-24.
干预措施: Lung function test (Device)
Rural houses
Rural Houses. Group of 40-60 rural houses, with 5 inhabitant per rural house. Expected number of participants: 200-300. Predicted number of non-smoker chronic respiratory disease of 12-18.
干预措施: Questionnaire (Other)
Rural houses
Rural Houses. Group of 40-60 rural houses, with 5 inhabitant per rural house. Expected number of participants: 200-300. Predicted number of non-smoker chronic respiratory disease of 12-18.
干预措施: Lung function test (Device)
结局指标
主要结局
FEV1/FVC
时间窗: 5 minutes
Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test. FEV1: forced expiratory volume in one second. FVC: Forced vital capacity.
FVC
时间窗: 5 minutes
Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes are performed during the same test.FVC: Forced vital capacity.
VC
时间窗: 5 minutes
Basic lung function test, without broncho dilatation (micro-spirometer). All lung function related outcomes performed during the same test. VC: Vital capacity
FEF 25-75%
时间窗: 5 minutes
Basic lung function test, without broncho dilatation (micro-spirometer).All lung function related outcomes are performed during the same test. FEF: Forced expiratory flow
Socio-demographic status
时间窗: around 10 minutes
Socio-demographic data, assessed by a home made questionnaire
Health status
时间窗: around 10 minutes
Health status (symptomatology) data, assessed by a home made questionnaire
Indoor air exposure time
时间窗: around 10 minutes
Indoor air exposure (time spent indoor within housing types, with associated air characteristics) data, assessed by a home made questionnaire
次要结局
未报告次要终点
研究者
Olivier Michel
Head of clinic
Brugmann University Hospital