Teledermatology and Modulation of Antibiotic Dose in Acne Vulgaris
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4
- 试验地点
- 2
- 主要终点
- Reduced antibiotic use
研究概览
简要总结
To see if teledermatology can be used to reduce antibiotic burden in patients on doxycycline or minocycline for acne vulgaris
详细描述
The investigators are going to ascertain if antibiotic burden can be reduced with tele dermatology use.
There are two arms of the study:
- Feedback group
- Non feedback group
All subjects will be randomised to either group, all subjects will take photos of their face and answer questions at baseline, visit 2 (1 month), visit 3 (2 months), visit 4 (3 months).
The investigators will then use measurements of acne grading (patient grading, investigator global assessment, lesion counting, global acne grading) to reduce/taper antibiotics in the feedback group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects aged 15 years and older
- •Subjects who have been prescribed doxycycline or minocycline by their physician for acne vulgaris but have not initiated treatment yet.
排除标准
- •Subjects who have used isotretinoin in the last 6 weeks
- •Those who have used oral antibiotics within the last 4 weeks
- •Those who have been initiated or changed brand of oral contraceptive pill within the last one month.
- •Those subjects who cannot engage with the teledermatology platform
- •Prisoners
- •Adults unable to consent
研究组 & 干预措施
Non Feedback
No feedback given to this group regarding their antibiotic use Subjects take images and answer questions during the study like the feedback group, but in this group no feedback re dosing is given.
干预措施: Non Feedback group (Other)
Feedback group
Feedback given to this group regarding their antibiotic use after baseline.
If the subject is in the feedback group, after this visit, a dermatologist will review all images and the survey results and give the patient information about whether they should:
- Continue current dose
- Reduce dose if there is at least a one point improvement in both the investigator acne global assessment AND the patient acne global assessment scores: A dose reduction will be such that the dose is halved from the previous dose. For example if the subject is on minocycline or doxycycline 100 mg twice daily, they will be reduced to minocycline or doxycycline 100 mg daily.
- Increase dose if had been previously reduced, dose will not be increased beyond the initial starting dose.
干预措施: Feedback group (Other)
结局指标
主要结局
Reduced antibiotic use
时间窗: Assessed at 4, 8, 12 weeks
The difference in antibiotic exposure in the physician feedback group compared to those not receiving feedback
次要结局
未报告次要终点