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Clinical Trials/NCT02529618
NCT02529618
Completed
Not Applicable

Implementation of iDETECT for Field Triage of mTBI in Football Players

Emory University4 sites in 1 country124 target enrollmentAugust 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Concussion
Sponsor
Emory University
Enrollment
124
Locations
4
Primary Endpoint
Area under the curve (AUC) for iDetect total score of neuropsychological assessment (NP) compared to the trainer's determination of clinical concussion
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The purpose of this study is to assess a new screening tool for sideline evaluation of concussion injuries in athletes. iDETECT is a new technology that combines several elements of recommended concussion screening tools into a single, portable device.

Detailed Description

The goal of the research is to evaluate the use of a multimodal platform (iDETECT) for immediate post-injury neuropsychological, balance and oculomotor assessment, and to evaluate the iDETECT platform as a return-to-play assessment tool during the post injury management period following concussion.

Registry
clinicaltrials.gov
Start Date
August 2015
End Date
February 2016
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Tamara Espinoza, MD

Assistant Professor

Emory University

Eligibility Criteria

Inclusion Criteria

  • Athletes participating in the Fall 2015 high school season
  • Aged 14 years or older
  • No concussion injuries within prior 2 months
  • Provide signed and data consent and/or assent form(s)

Exclusion Criteria

  • Non-English speaking
  • History of seizures or prior brain surgery (excluding facial and TM surgery)
  • Concussion within last 2 months
  • Poor Effort on baseline iDETECT test
  • Non-Collision Sport Group
  • current concussion or history of current concussion during the Fall 2015 athletic season

Outcomes

Primary Outcomes

Area under the curve (AUC) for iDetect total score of neuropsychological assessment (NP) compared to the trainer's determination of clinical concussion

Time Frame: Baseline, throughout duration of sport season (an expected average of 4 months)

The area under the receiver operator characteristic (ROC) curve (the concordance index) for total score of NP will be computed and compared with the trainer's determination of clinical concussion to find out if iDETECT is as accurate in diagnosing concussion.

Area under the curve (AUC) for iDetect NP total score compared to the Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) score

Time Frame: Baseline, throughout duration of sport season (an expected average of 4 months)

The area under the receiver operator characteristic (ROC) curve (the concordance index) for total score of NP will be computed and compared to the ImPACT score to find out if iDETECT is as accurate in diagnosing concussion.

Area under the curve (AUC) for iDetect NP response time to stimuli compared to the trainer's determination of clinical concussion

Time Frame: Baseline, throughout duration of sport season (an expected average of 4 months)

The area under the receiver operator characteristic (ROC) curve (the concordance index) for NP response will be computed and compared trainer's determination of clinical concussion to find out if iDETECT is as accurate in diagnosing concussion.

Area under the curve (AUC) for iDETECT total score compared to final clinical determination of concussion

Time Frame: Baseline, throughout duration of sport season (an expected average of 4 months)

The area under the receiver operator characteristic (ROC) curve (the concordance index) for iDETECT total score will be compared to the trainer's final clinical determination of concussion.

Area under the curve (AUC) for iDETECT total score compared to the Sport Concussion Assessment Tool (SCAT3)

Time Frame: Baseline, throughout duration of sport season (an expected average of 4 months)

The area under the receiver operator characteristic (ROC) curve (the concordance index) for iDETECT total score will be compared to the SCAT 3 score. SCAT3 is a standardized tool for evaluating injured athletes for concussion.

Area under the curve (AUC) for iDetect NP response time to stimuli compared to Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) score

Time Frame: Baseline, throughout duration of sport season (an expected average of 4 months)

The area under the receiver operator characteristic (ROC) curve (the concordance index) for NP response will be computed and compared the ImPACT score to find out if iDETECT is as accurate in diagnosing concussion.

Secondary Outcomes

  • Area under the curve (AUC) for iDETECT Non-postural Balance/Sensory Integration (SI) battery time to balance compared to trainer's determination of clinical concussion(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Area under the curve (AUC) for iDETECT Non-postural Balance/Sensory Integration (SI) battery time to balance compared to Balance Error Scoring System (BESS) score(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Area under the curve (AUC) for iDETECT Non-postural Balance/Sensory Integration (SI) battery number of overshoots compared to BESS score(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Area under the curve (AUC) for iDETECT Vestibular and Oculomotor (VO) battery angle difference in target motion prediction compared to trainer's determination of clinical concussion(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Area under the curve (AUC) for iDETECT Vestibular and Oculomotor (VO) battery angle difference in target motion prediction compared to King-Devick score (time and number of errors)(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Area under the curve (AUC) for iDETECT Vestibular and Oculomotor (VO) battery angle difference in target motion interefence compared to trainer's determination of clinical concussion(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Area under the curve (AUC) for iDETECT Vestibular and Oculomotor (VO) battery angle difference in target motion interefence compared to King-Devick score (time and number of errors)(Baseline, throughout duration of sport season (an expected average of 4 months))
  • Change in iDETECT total score from baseline to time of injury(Baseline, time of concussion)
  • Change in iDETECT total score from baseline to end of season to assess subconcussion(Baseline, end of sport season (an expected average of 4 months))
  • Change in Sport Concussion Assessment Tool 3 (SCAT3) total score from baseline to end of season to assess subconcussion(Baseline, end of sport season (an expected average of 4 months))
  • iDETECT word recall score post injury(3 days post injury (3 minutes))
  • Change in iDETECT mean word recall score post injury, 10 days(3 days post injury (3 minutes), 10 days post injury (3 minutes))
  • Change in iDETECT mean word recall score post injury, 30 days(10 days post injury (3 minutes), 30 days post injury (3 minutes))
  • iDETECT shapes test score post injury(3 days post injury (2 minutes))
  • Change in iDETECT mean shapes test score post injury, 10 days(3 days post injury (2 minutes), 10 days post injury (2 minutes))
  • Change in iDETECT mean shapes test score post injury, 30 days(10 days post injury (3 minutes), 30 days post injury (3 minutes))
  • iDETECT arrows test score post injury(3 days post injury (2 minutes))
  • Change in iDETECT mean arrows test score post injury, 10 days(3 days post injury (2 minutes), 10 days post injury (2 minutes))
  • Change in iDETECT mean arrows test score post injury, 30 days(10 days post injury (2 minutes), 30 days post injury (2 minutes))
  • iDETECT N-BACK (1-back and 2-back) test post injury(3 days post injury (2 minutes))
  • iDETECT Delayed Word Recall Test(3 days post injury (2 minutes))
  • Change in iDETECT Delayed Word Recall Test(10 days post injury (2 minutes), 30 days post injury (2 minutes))

Study Sites (4)

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